Uniprot ID	Q08828
Uniprot Name	ADCY1_HUMAN
Taxonomy ID	9606
Sequence	M A G A P R G G G G G G G G A G E P G G A E R A A G T S R R R G L R A C D E E F A C P E L E A L F R G Y T L R L E Q A A T L K A L A V L S L L A G A L A L A E L L G A P G P A P G L A K G S H P V H C V L F L A L L V V T N V R S L Q V P Q L Q Q V G Q L A L L F S L T F A L L C C P F A L G G P A R G S A G A A G G P A T A E Q G V W Q L L L V T F V S Y A L L P V R S L L A I G F G L V V A A S H L L V T A T L V P A K R P R L W R T L G A N A L L F V G V N M Y G V F V R I L T E R S Q R K A F L Q A R S C I E D R L R L E D E N E K Q E R L L M S L L P R N V A M E M K E D F L K P P E R I F H K I Y I Q R H D N V S I L F A D I V G F T G L A S Q C T A Q E L V K L L N E L F G K F D E L A T E N H C R R I K I L G D C Y Y C V S G L T Q P K T D H A H C C V E M G L D M I D T I T S V A E A T E V D L N M R V G L H T G R V L C G V L G L R K W Q Y D V W S N D V T L A N V M E A A G L P G K V H I T K T T L A C L N G D Y E V E P G Y G H E R N S F L K T H N I E T F F I V P S H R R K I F P G L I L S D I K P A K R M K F K T V C Y L L V Q L M H C R K M F K A E I P F S N V M T C E D D D K R R A L R T A S E K L R N R S S F S T N V V Y T T P G T R V N R Y I S R L L E A R Q T E L E M A D L N F F T L K Y K H V E R E Q K Y H Q L Q D E Y F T S A V V L T L I L A A L F G L V Y L L I F P Q S V V V L L L L V F C I C F L V A C V L Y L H I T R V Q C F P G C L T I Q I R T V L C I F I V V L I Y S V A Q G C V V G C L P W A W S S K P N S S L V V L S S G G Q R T A L P T L P C E S T H H A L L C C L V G T L P L A I F F R V S S L P K M I L L S G L T T S Y I L V L E L S G Y T R T G G G A V S G R S Y E P I V A I L L F S C A L A L H A R Q V D I R L R L D Y L W A A Q A E E E R E D M E K V K L D N R R I L F N L L P A H V A Q H F L M S N P R N M D L Y Y Q S Y S Q V G V M F A S I P N F N D F Y I E L D G N N M G V E C L R L L N E I I A D F D E L M E K D F Y K D I E K I K T I G S T Y M A A V G L A P T S G T K A K K S I S S H L S T L A D F A I E M F D V L D E I N Y Q S Y N D F V L R V G I N V G P V V A G V I G A R R P Q Y D I W G N T V N V A S R M D S T G V Q G R I Q V T E E V H R L L R R C P Y H F V C R G K V S V K G K G E M L T Y F L E G R T D G N G S Q I R S L G L D R K M C P F G R A G L Q G R R P P V C P M P G V S V R A G L P P H S P G Q Y L P S A A A G K E A
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250|UniProtKB:P19754}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250|UniProtKB:P19754}; Note=Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro). {ECO:0000250|UniProtKB:P30803};
Active site	No current data
Pfam	PF16214 PF00211
InterPro	IPR001054 IPR018297 IPR032628 IPR030672 IPR029787