Uniprot ID	Q12630
Uniprot Name	TKT1_KLULA
Taxonomy ID	284590
Sequence	M S Q Y T D I D R L A V S T I R L L A V D Q V S A A N S G H P G A P L G L A P A A H V I W K Q M R L N P K N P E W I N R D R F V L S N G H A C A L L Y S L L H L F G Y D M S I E D L K H F R H L G S K T P G H P E F E L P G V E V T T G P L G Q G I S N A V G M A I A Q A N F A A T Y N K P D Y E L S D S Y T Y V F L G D G C L Q E G V S S E A S S L A G H L R L K N L I A F Y D D N Q I T I D G N I N V S F D E D V S K R Y E A Y G W E V L H V E N G N D D L D A I S K A L E Q A K L S D R P T L I K L T T T I G F G S L N A G S H S V H G A P L K A D D V K Q L K V K F G F N P E E S F V V P Q E V Y D L Y N K S T I E P G I E A N K Q W D A L L D A Y V G Q F P E L G A E V K R R L A G E F P E G W E S K L P T Y T P E D S A V A S R K L S E I V L D N V F D T L P E L L G G S A D L T P S N L T R S K G A V D F Q P P I T G L G D Y S G R Y I R Y G V R E H G M G A I M N G I S A F G A N Y R P Y G G T F L N F V S Y A S G A V R L S A L S G H P V I W V A T H D S I G L G E D G P T H Q P I E T L A H F R A I P N L Q V W R P A D G N E V T A A Y K V A L T N K H T P A I I A L S R Q N L P Q L Q G S S V E K A V K G G Y I L Q D V D Q P D L A I V S T G S E V G I A V E A A K V L A E K N I K A R I V S L P D F H S F G Q Q S K E Y Q L S V F P D G V P I L S V E V L A T S G W S K Y A H Q S F G L D R F G A S G K G P A V Y E K F E F T P Q G I A T R A E K T V E F Y K G K Q V I S P L N T A F
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000250}; Note=Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+). {ECO:0000250}; COFACTOR: Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937; Evidence={ECO:0000250}; Note=Binds 1 thiamine pyrophosphate per subunit. {ECO:0000250};
Active site	ACT_SITE 417 417 Proton donor. {ECO:0000250}.
Pfam	PF02779 PF02780 PF00456
InterPro	IPR029061 IPR009014 IPR005475 IPR005478 IPR020826 IPR033248 IPR033247 IPR005474