Uniprot ID	Q12659
Uniprot Name	ARO1_PNECA
Taxonomy ID	4754
Sequence	M K E I I K L S I L G K D S I H I G L H L W P H I T N E L F T C I F S P T Y V I I T D S N I E T L Y I P S F K T Y F I S M A K Q R S I N S R L L F F T I P P G E K S K S R K T K A L I E D W L L S E K C T R D T V I I A I G G G V I G D L V G Y V S A T F M R G V R F I Q I P T T L L A M V D S S I G G K N S I N T S Y G K N A I G T I W Q P E R I F I D F T F L E T L T E K E F I N G I A E L I K T I I I W D E S E F A S L E N I S E K I A K T V R S M S L T S N K H S K F N E I I K D L K R Y I I S S I K I K A H I V S I D E K E K D L R T L L N F G H S I G H A I E T V L A P Y I L H G E S I S I G M V K E A E L S R H L G I L N P N V V S R L I K C L N T W G L P T S F K D R R F K E V I L G K K H L I E D I L E I M S I D K K N D S N N K K I V L L S A I G K T Y E K K A S S V S D D D I R T I L S Q N I L L Y G I P L N A F Q K H T T I T L P G S K S I S N R A L I L A S L S N G I C Y L K N F L H S D D T Y Y M L S A L E K L N A A E F K W E Q D G D V L V V K G K S G Y L E N P Q M E L Y L G N S G T T A R F L T S I C T L V Q P N S R E N H L I L T G S N R M K Q R P I G P L V D A L K N N G C C I E Y L E L E N C L P L L I K P K E I G L Y G G N I N L S A T V S S Q Y V S S I L M C S P Y A K T Q V T L S L I G G K P I S Q P Y I D M T I S M M S S F G I K V T R S H S K E N T Y Y I P K G C Y T C P S E Y I I E G D A T S A T Y P L A I A A I T G G S C T I S N V G S A S L Q G D S K F S E Y I L K P M G C E V V Q S P T T T Y I K G P P K G K L K S L G S I N M E S M T D T F L T A A V L A S V A Y E E S K P Y V T K I T G I S N Q R I K E C N R I N A M V C E L K K F G I E A G E L P D G I Y V K A L N T S N L P Y S V E G I N C Y N D H R I A M S F S V L A C I S S K P T T I L D K A C V N K T W P Y W W D I L N S T F K V Q M K G I E F D L N P T I N S S I L H H P S E C T I F L I G M R G A G K T T L G Q L A A N F L G R E F I D L D S I I E E D I K T T I L E F I Q K Y S W D V F R R K E L H F L K T L L T E K K E N Y I I S C G G G I I E T E E A R D L L I S Y I E A N G I V I H I H R N I Q D I I K Y L N T D K T R A P Y Q D N I M H V W E R R K R W Y N L C S S H Q F H M T S T D P T E F K K N I P L N L K S S F N N F L R T I T G K N N I F S L I L K K K R S Y F L S L A F S D L E N I F S L L D I I T A G C D A I E I R I D L F Q K P E E I D K Y P S L E Y I A E K I F L L R Q K T S L P L I Y T L R T T N H G G S F L S S E K K L A K E Y I L H G A K W G F E F L D I E L D I A S E L F K T I N N S W P Y T K I I A S Y H N I E K P I S C D D F E W I Q K Y K E A Q H Y G H I I K L V G T S S S I E D N F F L E E F K S K F I N K K V P S I I I N T G I K G Q L S R I M N T F M T P V T H P S L P S K I A P G Q L S I K E I N T A L H I M G L L P E K K Y F L F G K P I K H S Q S P N I H N L G F E I L G L P Y K Y Q L F E T D S I S E L K E I L H L E E F G G A S V T I P L K T N I S I L L D E I S D H A A L I G S V N T I T R T Y N N G Q Y I L K G E N T D W Q G I I K A I K N F N K F E K S F E N F S G F I I G A G G A S R A A I Y A L L S L G I S P I Y L I N R S K D K L N K L Y H F F N T N H I I P I T E Y H E L N N I N F D I R I G I S T I P T D N P I D P S V L E I A K I F F N L K R K S S E G I F L D M A Y G S N T T D L T I I A K A C N W K I I H G L E I L L E Q G S E Q F L L W T E T Y I P Y N Q V K Y A I L G P N K
Cofactor	COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000255|HAMAP-Rule:MF_03143}; Note=Binds 2 Zn(2+) ions per subunit. {ECO:0000255|HAMAP-Rule:MF_03143};
Active site	ACT_SITE 259 259 Proton acceptor; for 3-dehydroquinate synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 274 274 Proton acceptor; for 3-dehydroquinate synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 827 827 For EPSP synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 1189 1189 Proton acceptor; for 3-dehydroquinate dehydratase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 1217 1217 Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.
Pfam	PF01761 PF01487 PF00275 PF08501 PF01202
InterPro	IPR018508 IPR013785 IPR016037 IPR030960 IPR001381 IPR001986 IPR036968 IPR006264 IPR023193 IPR036291 IPR027417 IPR008289 IPR013792 IPR031322 IPR013708 IPR010110 IPR000623 IPR023000