Uniprot ID	Q13370
Uniprot Name	PDE3B_HUMAN
Taxonomy ID	9606
Sequence	M R R D E R D A K A M R S L Q P P D G A G S P P E S L R N G Y V K S C V S P L R Q D P P R G F F F H L C R F C N V E L R P P P A S P Q Q P R R C S P F C R A R L S L G A L A A F V L A L L L G A E P E S W A A G A A W L R T L L S V C S H S L S P L F S I A C A F F F L T C F L T R T K R G P G P G R S C G S W W L L A L P A C C Y L G D F L V W Q W W S W P W G D G D A G S A A P H T P P E A A A G R L L L V L S C V G L L L T L A H P L R L R H C V L V L L L A S F V W W V S F T S L G S L P S A L R P L L S G L V G G A G C L L A L G L D H F F Q I R E A P L H P R L S S A A E E K V P V I R P R R R S S C V S L G E T A A S Y Y G S C K I F R R P S L P C I S R E Q M I L W D W D L K Q W Y K P H Y Q N S G G G N G V D L S V L N E A R N M V S D L L T D P S L P P Q V I S S L R S I S S L M G A F S G S C R P K I N P L T P F P G F Y P C S E I E D P A E K G D R K L N K G L N R N S L P T P Q L R R S S G T S G L L P V E Q S S R W D R N N G K R P H Q E F G I S S Q G C Y L N G P F N S N L L T I P K Q R S S S V S L T H H V G L R R A G V L S S L S P V N S S N H G P V S T G S L T N R S P I E F P D T A D F L N K P S V I L Q R S L G N A P N T P D F Y Q Q L R N S D S N L C N S C G H Q M L K Y V S T S E S D G T D C C S G K S G E E E N I F S K E S F K L M E T Q Q E E E T E K K D S R K L F Q E G D K W L T E E A Q S E Q Q T N I E Q E V S L D L I L V E E Y D S L I E K M S N W N F P I F E L V E K M G E K S G R I L S Q V M Y T L F Q D T G L L E I F K I P T Q Q F M N Y F R A L E N G Y R D I P Y H N R I H A T D V L H A V W Y L T T R P V P G L Q Q I H N G C G T G N E T D S D G R I N H G R I A Y I S S K S C S N P D E S Y G C L S S N I P A L E L M A L Y V A A A M H D Y D H P G R T N A F L V A T N A P Q A V L Y N D R S V L E N H H A A S A W N L Y L S R P E Y N F L L H L D H V E F K R F R F L V I E A I L A T D L K K H F D F L A E F N A K A N D V N S N G I E W S N E N D R L L V C Q V C I K L A D I N G P A K V R D L H L K W T E G I V N E F Y E Q G D E E A N L G L P I S P F M D R S S P Q L A K L Q E S F I T H I V G P L C N S Y D A A G L L P G Q W L E A E E D N D T E S G D D E D G E E L D T E D E E M E N N L N P K P P R R K S R R R I F C Q L M H H L T E N H K I W K E I V E E E E K C K A D G N K L Q V E N S S L P Q A D E I Q V I E E A D E E E
Cofactor	COFACTOR: Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; Evidence={ECO:0000269|PubMed:15147193}; Note=Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. {ECO:0000269|PubMed:15147193};
Active site	ACT_SITE 737 737 Proton donor. {ECO:0000250}.
Pfam	PF00233
InterPro	IPR003607 IPR002073 IPR036971 IPR023174