Uniprot ID	Q14432
Uniprot Name	PDE3A_HUMAN
Taxonomy ID	9606
Sequence	M A V P G D A A R V R D K P V H S G V S Q A P T A G R D C H H R A D P A S P R D S G C R G C W G D L V L Q P L R S S R K L S S A L C A G S L S F L L A L L V R L V R G E V G C D L E Q C K E A A A A E E E E A A P G A E G G V F P G P R G G A P G G G A R L S P W L Q P S A L L F S L L C A F F W M G L Y L L R A G V R L P L A V A L L A A C C G G E A L V Q I G L G V G E D H L L S L P A A G V V L S C L A A A T W L V L R L R L G V L M I A L T S A V R T V S L I S L E R F K V A W R P Y L A Y L A G V L G I L L A R Y V E Q I L P Q S A E A A P R E H L G S Q L I A G T K E D I P V F K R R R R S S S V V S A E M S G C S S K S H R R T S L P C I P R E Q L M G H S E W D H K R G P R G S Q S S G T S I T V D I A V M G E A H G L I T D L L A D P S L P P N V C T S L R A V S N L L S T Q L T F Q A I H K P R V N P V T S L S E N Y T C S D S E E S S E K D K L A I P K R L R R S L P P G L L R R V S S T W T T T T S A T G L P T L E P A P V R R D R S T S I K L Q E A P S S S P D S W N N P V M M T L T K S R S F T S S Y A I S A A N H V K A K K Q S R P G A L A K I S P L S S P C S S P L Q G T P A S S L V S K I S A V Q F P E S A D T T A K Q S L G S H R A L T Y T Q S A P D L S P Q I L T P P V I C S S C G R P Y S Q G N P A D E P L E R S G V A T R T P S R T D D T A Q V T S D Y E T N N N S D S S D I V Q N E D E T E C L R E P L R K A S A C S T Y A P E T M M F L D K P I L A P E P L V M D N L D S I M E Q L N T W N F P I F D L V E N I G R K C G R I L S Q V S Y R L F E D M G L F E A F K I P I R E F M N Y F H A L E I G Y R D I P Y H N R I H A T D V L H A V W Y L T T Q P I P G L S T V I N D H G S T S D S D S D S G F T H G H M G Y V F S K T Y N V T D D K Y G C L S G N I P A L E L M A L Y V A A A M H D Y D H P G R T N A F L V A T S A P Q A V L Y N D R S V L E N H H A A A A W N L F M S R P E Y N F L I N L D H V E F K H F R F L V I E A I L A T D L K K H F D F V A K F N G K V N D D V G I D W T N E N D R L L V C Q M C I K L A D I N G P A K C K E L H L Q W T D G I V N E F Y E Q G D E E A S L G L P I S P F M D R S A P Q L A N L Q E S F I S H I V G P L C N S Y D S A G L M P G K W V E D S D E S G D T D D P E E E E E E A P A P N E E E T C E N N E S P K K K T F K R R K I Y C Q I T Q H L L Q N H K M W K K V I E E E Q R L A G I E N Q S L D Q T P Q S H S S E Q I Q A I K E E E E E K G K P R G E E I P T Q K P D Q
Cofactor	COFACTOR: Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; Evidence={ECO:0000250}; Note=Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. {ECO:0000250};
Active site	ACT_SITE 752 752 Proton donor. {ECO:0000250}.
Pfam	PF00233
InterPro	IPR003607 IPR002073 IPR036971 IPR023174