Uniprot ID	Q15751
Uniprot Name	HERC1_HUMAN
Taxonomy ID	9606
Sequence	M A T M I P P V K L K W L E H L N S S W I T E D S E S I A T R E G V A V L Y S K L V S N K E V V P L P Q Q V L C L K G P Q L P D F E R E S L S S D E Q D H Y L D A L L S S Q L A L A K M V C S D S P F A G A L R K R L L V L Q R V F Y A L S N K Y H D K G K V K Q Q Q H S P E S S S G S A D V H S V S E R P R S S T D A L I E M G V R T G L S L L F A L L R Q S W M M P V S G P G L S L C N D V I H T A I E V V S S L P P L S L A N E S K I P P M G L D C L S Q V T T F L K G V T I P N S G A D T L G R R L A S E L L L G L A A Q R G S L R Y L L E W I E M A L G A S A V V H T M E K G K L L S S Q E G M I S F D C F M T I L M Q M R R S L G S S A D R S Q W R E P T R T S D G L C S L Y E A A L C L F E E V C R M A S D Y S R T C A S P D S I Q T G D A P I V S E T C E V Y V W G S N S S H Q L V E G T Q E K I L Q P K L A P S F S D A Q T I E A G Q Y C T F V I S T D G S V R A C G K G S Y G R L G L G D S N N Q S T L K K L T F E P H R S I K K V S S S K G S D G H T L A F T T E G E V F S W G D G D Y G K L G H G N S S T Q K Y P K L I Q G P L Q G K V V V C V S A G Y R H S A A V T E D G E L Y T W G E G D F G R L G H G D S N S R N I P T L V K D I S N V G E V S C G S S H T I A L S K D G R T V W S F G G G D N G K L G H G D T N R V Y K P K V I E A L Q G M F I R K V C A G S Q S S L A L T S T G Q V Y A W G C G A C L G C G S S E A T A L R P K L I E E L A A T R I V D V S I G D S H C L A L S H D N E V Y A W G N N S M G Q C G Q G N S T G P I T K P K K V S G L D G I A I Q Q I S A G T S H S L A W T A L P R D R Q V V A W H R P Y C V D L E E S T F S H L R S F L E R Y C D K I N S E I P P L P F P S S R E H H S F L K L C L K L L S N H L A L A L A G G V A T S I L G R Q A G P L R N L L F R L M D S T V P D E I Q E V V I E T L S V G A T M L L P P L R E R M E L L H S L L P Q G P D R W E S L S K G Q R M Q L D I I L T S L Q D H T H V A S L L G Y S S P S D A A D L S S V C T G Y G N L S D Q P Y G T Q S C H P D T H L A E I L M K T L L R N L G F Y T D Q A F G E L E K N S D K F L L G T S S S E N S Q P A H L H E L L C S L Q K Q L L A F C H I N N I S E N S S S V A L L H K H L Q L L L P H A T D I Y S R S A N L L K E S P W N G S V G E K L R D V I Y V S A A G S M L C Q I V N S L L L L P V S V A R P L L S Y L L D L L P P L D C L N R L L P A A D L L E D Q E L Q W P L H G G P E L I D P A G L P L P Q P A Q S W V W L V D L E R T I A L L I G R C L G G M L Q G S P V S P E E Q D T A Y W M K T P L F S D G V E M D T P Q L D K C M S C L L E V A L S G N E E Q K P F D Y K L R P E I A V Y V D L A L G C S K E P A R S L W I S M Q D Y A V S K D W D S A T L S N E S L L D T V S R F V L A A L L K H T N L L S Q A C G E S R Y Q P G K H L S E V Y R C V Y K V R S R L L A C K N L E L I Q T R S S S R D R W I S E N Q D S A D V D P Q E H S F T R T I D E E A E M E E Q A E R D R E E G H P E P E D E E E E R E H E V M T A G K I F Q C F L S A R E V A R S R D R D R M N S G A G S G A R A D D P P P Q S Q Q E R R V S T D L P E G Q D V Y T A A C N S V I H R C A L L I L G V S P V I D E L Q K R R E E G Q L Q Q P S T S A S E G G G L M T R S E S L T A E S R L V H T S P N Y R L I K S R S E S D L S Q P E S D E E G Y A L S G R R N V D L D L A A S H R K R G P M H S Q L E S L S D S W A R L K H S R D W L C N S S Y S F E S D F D L T K S L G V H T L I E N V V S F V S G D V G N A P G F K E P E E S M S T S P Q A S I I A M E Q Q Q L R A E L R L E A L H Q I L V L L S G M E E K G S I S L A G S R L S S G F Q S S T L L T S V R L Q F L A G C F G L G T V G H T G G K G E S G R L H H Y Q D G I R A A K R N I Q I E I Q V A V H K I Y Q Q L S A T L E R A L Q A N K H H I E A Q Q R L L L V T V F A L S V H Y Q P V D V S L A I S T G L L N V L S Q L C G T D T M L G Q P L Q L L P K T G V S Q L S T A L K V A S T R L L Q I L A I T T G T Y A D K L S P K V V Q S L L D L L C S Q L K N L L S Q T G V L H M A S F G E G E Q E D G E E E E K K V D S S G E T E K K D F R A A L R K Q H A A E L H L G D F L V F L R R V V S S K A I Q S K M A S P K W T E V L L N I A S Q K C S S G I P L V G N L R T R L L A L H V L E A V L P A C E S G V E D D Q M A Q I V E R L F S L L S D C M W E T P I A Q A K H A I Q I K E K E Q E I K L Q K Q G E L E E E D E N L P I Q E V S F D P E K A Q C C L V E N G Q I L T H G S G G K G Y G L A S T G V T S G C Y Q W K F Y I V K E N R G N E G T C V G V S R W P V H D F N H R T T S D M W L Y R A Y S G N L Y H N G E Q T L T L S S F T Q G D F I T C V L D M E A R T I S F G K N G E E P K L A F E D V D A A E L Y P C V M F Y S S N P G E K V K I C D M Q M R G T P R D L L P G D P I C S P V A A V L A E A T I Q L I R I L H R T D R W T Y C I N K K M M E R L H K I K I C I K E S G Q K L K K S R S V Q S R E E N E M R E E K E S K E E E K G K H T R H G L A D L S E L Q L R T L C I E V W P V L A V I G G V D A G L R V G G R C V H K Q T G R H A T L L G V V K E G S T S A K V Q W D E A E I T I S F P T F W S P S D T P L Y N L E P C E P L P F D V A R F R G L T A S V L L D L T Y L T G V H E D M G K Q S T K R H E K K H R H E S E E K G D V E Q K P E S E S A L D M R T G L T S D D V K S Q S T T S S K S E N E I A S F S L D P T L P S V E S Q H Q I T E G K R K N H E H M S K N H D V A Q S E I R A V Q L S Y L Y L G A M K S L S A L L G C S K Y A E L L L I P K V L A E N G H N S D C A S S P V V H E D V E M R A A L Q F L M R H M V K R A V M R S P I K R A L G L A D L E R A Q A M I Y K L V V H G L L E D Q F G G K I K Q E I D Q Q A E E S D P A Q Q A Q T P V T T S P S A S S T T S F M S S S L E D T T T A T T P V T D T E T V P A S E S P G V M P L S L L R Q M F S S Y P T T T V L P T R R A Q T P P I S S L P T S P S D E V G R R Q S L T S P D S Q S A R P A N R T A L S D P S S R L S T S P P P P A I A V P L L E M G F S L R Q I A K A M E A T G A R G E A D A Q N I T V L A M W M I E H P G H E D E E E P Q S G S T A D S R P G A A V L G S G G K S N D P C Y L Q S P G D I P S A D A A E M E E G F S E S P D N L D H T E N A A S G S G P S A R G R S A V T R R H K F D L A A R T L L A R A A G L Y R S V Q A H R N Q S R R E G I S L Q Q D P G A L Y D F N L D E E L E I D L D D E A M E A M F G Q D L T S D N D I L G M W I P E V L D W P T W H V C E S E D R E E V V V C E L C E C S V V S F N Q H M K R N H P G C G R S A N R Q G Y R S N G S Y V D G W F G G E C G S G N P Y Y L L C G T C R E K Y L A M K T K S K S T S S E R Y K G Q A P D L I G K Q D S V Y E E D W D M L D V D E D E K L T G E E E F E L L A G P L G L N D R R I V P E P V Q F P D S D P L G A S V A M V T A T N S M E E T L M Q I G C H G S V E K S S S G R I T L G E Q A A A L A N P H D R V V A L R R V T A A A Q V L L A R T M V M R A L S L L S V S G S S C S L A A G L E S L G L T D I R T L V R L M C L A A A G R A G L S T S P S A M A S T S E R S R G G H S K A N K P I S C L A Y L S T A V G C L A S N A P S A A K L L V Q L C T Q N L I S A A T G V N L T T V D D S I Q R K F L P S F L R G I A E E N K L V T S P N F V V T Q A L V A L L A D K G A K L R P N Y D K S E V E K K G P L E L A N A L A A C C L S S R L S S Q H R Q W A A Q Q L V R T L A A H D R D N Q T T L Q T L A D M G G D L R K C S F I K L E A H Q N R V M T C V W C N K K G L L A T S G N D G T I R V W N V T K K Q Y S L Q Q T C V F N R L E G D A E E S L G S P S D P S F S P V S W S I S G K Y L A G A L E K M V N I W Q V N G G K G L V D I Q P H W V S A L A W P E E G P A T A W S G E S P E L L L V G R M D G S L G L I E V V D V S T M H R R E L E H C Y R K D V S V T C I A W F S E D R P F A V G Y F D G K L L L G T K E P L E K G G I V L I D A H K D T L I S M K W D P T G H I L M T C A K E D S V K L W G S I S G C W C C L H S L C H P S I V N G I A W C R L P G K G S K L Q L L M A T G C Q S G L V C V W R I P Q D T T Q T N V T S A E G W W E Q E S N C Q D G Y R K S S G A K C V Y Q L R G H I T P V R T V A F S S D G L A L V S G G L G G L M N I W S L R D G S V L Q T V V I G S G A I Q T T V W I P E V G V A A C S N R S K D V L V V N C T A E W A A A N H V L A T C R T A L K Q Q G V L G L N M A P C M R A F L E R L P M M L Q E Q Y A Y E K P H V V C G D Q L V H S P Y M Q C L A S L A V G L H L D Q L L C N P P V P P H H Q N C L P D P A S W N P N E W A W L E C F S T T I K A A E A L T N G A Q F P E S F T V P D L E P V P E D E L V F L M D N S K W I N G M D E Q I M S W A T S R P E D W H L G G K C D V Y L W G A G R H G Q L A E A G R N V M V P A A A P S F S Q A Q Q V I C G Q N C T F V I Q A N G T V L A C G E G S Y G R L G Q G N S D D L H V L T V I S A L Q G F V V T Q L V T S C G S D G H S M A L T E S G E V F S W G D G D Y G K L G H G N S D R Q R R P R Q I E A L Q G E E V V Q M S C G F K H S A V V T S D G K L F T F G N G D Y G R L G L G N T S N K K L P E R V T A L E G Y Q I G Q V A C G L N H T L A V S A D G S M V W A F G D G D Y G K L G L G N S T A K S S P Q K I D V L C G I G I K K V A C G T Q F S V A L T K D G H V Y T F G Q D R L I G L P E G R A R N H N R P Q Q I P V L A G V I I E D V A V G A E H T L A L A S N G D V Y A W G S N S E G Q L G L G H T N H V R E P T L V T G L Q G K N V R Q I S A G R C H S A A W T A P P V P P R A P G V S V P L Q L G L P D T V P P Q Y G A L R E V S I H T V R A R L R L L Y H F S D L M Y S S W R L L N L S P N N Q N S T S H Y N A G T W G I V Q G Q L R P L L A P R V Y T L P M V R S I G K T M V Q G K N Y G P Q I T V K R I S T R G R K C K P I F V Q I A R Q V V K L N A S D L R L P S R A W K V K L V G E G A D D A G G V F D D T I T E M C Q E L E T G I V D L L I P S P N A T A E V G Y N R D R F L F N P S A C L D E H L M Q F K F L G I L M G V A I R T K K P L D L H L A P L V W K Q L C C V P L T L E D L E E V D L L Y V Q T L N S I L H I E D S G I T E E S F H E M I P L D S F V G Q S A D G K M V P I I P G G N S I P L T F S N R K E Y V E R A I E Y R L H E M D R Q V A A V R E G M S W I V P V P L L S L L T A K Q L E Q M V C G M P E I S V E V L K K V V R Y R E V D E Q H Q L V Q W F W H T L E E F S N E E R V L F M R F V S G R S R L P A N T A D I S Q R F Q I M K V D R P Y D S L P T S Q T C F F Q L R L P P Y S S Q L V M A E R L R Y A I N N C R S I D M D N Y M L S R N V D N A E G S D T D Y
Cofactor	No current data
Active site	ACT_SITE 4811 4811 Glycyl thioester intermediate. {ECO:0000255|PROSITE-ProRule:PRU00104}.
Pfam	PF00632 PF00415 PF00622 PF00400
InterPro	IPR001870 IPR013320 IPR000569 IPR035983 IPR009091 IPR000408 IPR003877 IPR035768 IPR015943 IPR001680 IPR019775 IPR017986 IPR036322