Uniprot ID	Q1RIM1
Uniprot Name	TOP1_RICBR
Taxonomy ID	336407
Sequence	M K L V I V E S P A K A K T I N K Y L G D E F K V I A S F G H I R D L P S K K G S V I P D E N F S M K Y D I S E K A G K Y V D A I I K D A K K A E S V Y L A T D P D R E G E S I S W H I A E V I K E K N K V K S D D F F K R V A F N E I T K K A I T H A I E N P R K L D N N L V N A Q Q A R R A L D Y L V G F T L S P L L W R K L P G C K S A G R V Q S V A L R L I C E R E D E I E R F K S E E Y W D I S L K M L N S N N E L F T A K L T H I N D Q K L E K F S I T N D K E A K D L T E K L K S Q N F H V D K I E K K Q Q K R Q P Q P P F I T S S L Q Q E A A R K L G F S A K K T M Q I A Q K L Y E G V D I G K E T I G L I T Y M R T D G V T L S N D A V D E I R K L I N K D Y G D K Y L P S S P R I Y K S K V K N A Q E A H E A I R P T N I N Y I P N D L K E K L E K D Y Y K L Y E L I W K R T I A C Q M E N V I M D L V N A T L A S E N K E Y L A R A N G S T I A F D G F Y K V Y R E S I D D E A E E E N K M L P P L K E Q E H L K T K E I I P N Q H F T E P P P R Y S E A S L V K K L E E L G I G R P S T Y A T I L S V L Q D R K Y V T L E K K R F I P E E L G R L V T V F L V G F F K K Y V E Y D F T A G L E N E L D E I A A G K L E W K S A L G N F W N G F N H N I E S V N K Q N I T E I I S Y V Q Q A L D Y H I F G E N K D S K V C P S C K T G E L S L K L G K F G A F L A C S N Y P E C N F R K S I V S G N D N N E A D G E A K D I V N E N K V L G K D K E G I E I Y L K K G P Y G P Y I Q Y G E Q V D S K I K P K R S P L P A G L N Q N D I T L D M A L K L L S L P L K I G N H K E S G E E V L V G Y G K F G P Y I K Y M G K F I S I P K K Y D F L N L S L D D A M K L I E E K L N A I A A K Q P N P L N M D E V T N L V D K K I K V K K T K K
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000255|HAMAP-Rule:MF_00952}; Note=Binds two Mg(2+) per subunit. {ECO:0000255|HAMAP-Rule:MF_00952};
Active site	ACT_SITE 304 304 O-(5'-phospho-DNA)-tyrosine intermediate. {ECO:0000255|HAMAP-Rule:MF_00952}.
Pfam	PF01131 PF01751 PF13368 PF01396
InterPro	IPR000380 IPR003601 IPR023406 IPR013497 IPR013824 IPR013825 IPR013826 IPR023405 IPR003602 IPR013498 IPR005733 IPR028612 IPR025589 IPR006171 IPR034149