Uniprot ID	Q22000
Uniprot Name	PDE4_CAEEL
Taxonomy ID	6239
Sequence	M P R R R G S S S S S S A A G G S G G G G G F G F S S L R R E L H L H N F F R T S S P S A S S T S R T P P A A L P P R T S A V T I P G S N H K L T S S A S S Y H P P R E L T V S T F S A G S A T A A D G L G G A H L T P S L S S S V H A R R E S F L Y R A S D D L R E A S S L R P V S R A S S I A S N E H G H G D D L I V T P F A Q L L A S L R N V R S N L I S I T N I Q N S D D S R H A N R S A K R P P L H N I E L P D D V V H C A H D T L E E L D W C L D Q L E T I Q T H R S V S E M A S S K F R K M L N K E L S H F A E S S K S G T Q V S K F L I T T Y M D K E E D E P S I E I E V P T E V Q G P S T S G P M T L S I L K K A Q T A A M N K I S G V R K L R A P S H D G H V P E Y G V N C A R E I A V H M Q R L D D W G P D V F K I D E L S K N H S L T V V T F S L L R Q R N L F K T F E I H Q S T L V T Y L L N L E H H Y R N N H Y H N F I H A A D V A Q S M H V L L M S P V L T E V F T D L E V L A A I F A G A V H D V D H P G F T N Q Y L I N S N N E L A I M Y N D E S V L E Q H H L A V A F K L L Q D S N C D F L A N L S R K Q R L Q F R K I V I D M V L A T D M S K H M S L L A D L K T M V E A K K V A G N N V I V L D K Y N D K I Q V L Q S M I H L A D L S N P T K P I E L Y Q Q W N Q R I M E E Y W R Q G D K E K E L G L E I S P M C D R G N V T I E K S Q V G F I D Y I V H P L Y E T W A D L V Y P D A Q N I L D Q L E E N R E W Y Q S R I P E E P D T A R T V T E D D E H K
Cofactor	COFACTOR: Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; Evidence={ECO:0000250}; Note=Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. {ECO:0000250};
Active site	ACT_SITE 407 407 Proton donor. {ECO:0000250}.
Pfam	PF18100 PF00233
InterPro	IPR003607 IPR040844 IPR023088 IPR002073 IPR036971 IPR023174