Uniprot ID	Q2NKZ4
Uniprot Name	TKTL2_BOVIN
Taxonomy ID	9913
Sequence	M A D S A T L D A T T V Q V L Q D L A N R L R V H S I R A T C A S G S G H P T S C C S A A E I V S V L F F H T M R Y R Q T E P A H P D N D R F V L S K G H A A P L L Y A A W V E A G S I S E P D L L N L R T I H C D L E G H P T P R L S F V D V A T G S L G Q G L G A A C G M A Y T G K Y L D K A S Y R V F C L L G D G E S S E G S V W E A L A F A S H Y G L D N L V A V F D V N R L G Q S G V A P L K H C T D I Y R N R C E A F G W N T Y L V D G H D V E A L C Q A F S Q A A Q G K N K P T A I I A K T Y K G R G I P N V E D A E N W H G K P L P K E R A D E I I R L I K S Q I K T N R N L L P K P P V E G S P P V S I T N I K M T C L P D Y K V G D K V A T Q K A Y G L A L A K L G L A N E R V V V L D G D P K N S T F F E I F K K E H P E R F I E C F A A E Q N M V S V A L G C A T R G R T I T F V T T L G A F L T R A F D Q I R M G A I S Q S N I N L I G S H C G V S V G E D G P S Q M A L E D L A M F R S I P N C T V F L P S D A V S T E H A V Y L A A N S E G M C F I R T N R S E T A V I Y T P Q E H F E I G R A K V I R H S N N D K V T V I G A G V T L H E A L A A A D A L S Q Q D I S I C V I D P F T I K P L D A A T I I S C A K A T D G R V V T V E D H Y Q E G G I G E A V C A A V S G E P A I H V H Q L S V S G V S E R N R K P S E L L S I F G V S A R H I I A A V K Y T L M N
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000250}; Note=Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+). {ECO:0000250}; COFACTOR: Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937; Evidence={ECO:0000250}; Note=Binds 1 thiamine pyrophosphate per subunit. {ECO:0000250};
Active site	ACT_SITE 369 369 Proton donor. {ECO:0000250}.
Pfam	PF02779 PF02780 PF00456
InterPro	IPR029061 IPR009014 IPR005475 IPR020826 IPR033248 IPR005474