Uniprot ID	Q2NL26
Uniprot Name	TKTL1_BOVIN
Taxonomy ID	9913
Sequence	M A D A E A S A T M A D E A K P D S K T L Q I L R D M A N R L R I H S I R A T C A S S S G H P I S C S S A A E I M S V L F F H V M R Y K Q A D P K N P D N D R F I L S K R L S F V D V A T G W L G Q G L G A A C G M A Y T G K Y F D K A S Y R V F C L V G D V E S W E G S V W E A L A F A S H Y S L D N L V A I F D V N R L T H S T T L P L E H S I D V Y Q K R C E A F G W N T L V V D G R D V E A L C Q V F W Q A A Q M K N K P T A V V A K T F K G R G I P S V E D A E N W H G K P M P K E R A D A I I K L I E S Q I E T N K S L E P K A P I E D S P Q I N I S V I E M T S P P D Y E I S D V I A T R K A C G L A L A K L G H A N D R V I V L D G D T K N S T F S D I F K R E H P E R F I E C F I A E Q N M V S V A L G C V T R G R T V A F A C T F A A F L T R A F D Q I R M G G I S Q T N I N L I G S H C G V S I G E D G P S Q M A L E D L A M F R A I P N C T I F Y P S D A I S T E H A V F L A A N I K G M C Y I R T S R P E T A I I Y T P Q E S F E I G Q A K V I R Q S V N D K I T V V G A G I T L H E A L A A A D D L S K Q G I S L R V I D L F T V K P L D A A T I I S N A K A T G G Q I I T V E D H Y P E G G I G E A V S A A V S M E P D I V V H H L A V S G I P R S G K P S D L L D M F G I S S K H I I W A V E R I L M K
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000250}; Note=Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+). {ECO:0000250}; COFACTOR: Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937; Evidence={ECO:0000250}; Note=Binds 1 thiamine pyrophosphate per subunit. {ECO:0000250};
Active site	ACT_SITE 340 340 Proton donor. {ECO:0000250}.
Pfam	PF02779 PF02780 PF00456
InterPro	IPR029061 IPR009014 IPR005475 IPR020826 IPR033248 IPR005474