Uniprot ID	Q38SD2
Uniprot Name	LRRK1_HUMAN
Taxonomy ID	9606
Sequence	M A G M S Q R P P S M Y W C V G P E E S A V C P E R A M E T L N G A G D T G G K P S T R G G D P A A R S R R T E G I R A A Y R R G D R G G A R D L L E E A C D Q C A S Q L E K G Q L L S I P A A Y G D L E M V R Y L L S K R L V E L P T E P T D D N P A V V A A Y F G H T A V V Q E L L E S L P G P C S P Q R L L N W M L A L A C Q R G H L G V V K L L V L T H G A D P E S Y A V R K N E F P V I V R L P L Y A A I K S G N E D I A I F L L R H G A Y F C S Y I L L D S P D P S K H L L R K Y F I E A S P L P S S Y P G K T A L R V K W S H L R L P W V D L D W L I D I S C Q I T E L D L S A N C L A T L P S V I P W G L I N L R K L N L S D N H L G E L P G V Q S S D E I I C S R L L E I D I S S N K L S H L P P G F L H L S K L Q K L T A S K N C L E K L F E E E N A T N W I G L R K L Q E L D I S D N K L T E L P A L F L H S F K S L N S L N V S R N N L K V F P D P W A C P L K C C K A S R N A L E C L P D K M A V F W K N H L K D V D F S E N A L K E V P L G L F Q L D A L M F L R L Q G N Q L A A L P P Q E K W T C R Q L K T L D L S R N Q L G K N E D G L K T K R I A F F T T R G R Q R S G T E A A S V L E F P A F L S E S L E V L C L N D N H L D T V P P S V C L L K S L S E L Y L G N N P G L R E L P P E L G Q L G N L W Q L D T E D L T I S N V P A E I Q K E G P K A M L S Y L R A Q L R K A E K C K L M K M I I V G P P R Q G K S T L L E I L Q T G R A P Q V V H G E A T I R T T K W E L Q R P A G S R A K V E S V E F N V W D I G G P A S M A T V N Q C F F T D K A L Y V V V W N L A L G E E A V A N L Q F W L L N I E A K A P N A V V L V V G T H L D L I E A K F R V E R I A T L R A Y V L A L C R S P S G S R A T G F P D I T F K H L H E I S C K S L E G Q E G L R Q L I F H V T C S M K D V G S T I G C Q R L A G R L I P R S Y L S L Q E A V L A E Q Q R R S R D D D V Q Y L T D R Q L E Q L V E Q T P D N D I K D Y E D L Q S A I S F L I E T G T L L H F P D T S H G L R N L Y F L D P I W L S E C L Q R I F N I K G S R S V A K N G V I R A E D L R M L L V G T G F T Q Q T E E Q Y F Q F L A K F E I A L P V A N D S Y L L P H L L P S K P G L D T H G M R H P T A N T I Q R V F K M S F V P V G F W Q R F I A R M L I S L A E M D L Q L F E N K K N T K S R N R K V T I Y S F T G N Q R N R C S T F R V K R N Q T I Y W Q E G L L V T F D G G Y L S V E S S D V N W K K K K S G G M K I V C Q S E V R D F S A M A F I T D H V N S L I D Q W F P A L T A T E S D G T P L M E Q Y V P C P V C E T A W A Q H T D P S E K S E D V Q Y F D M E D C V L T A I E R D F I S C P R H P D L P V P L Q E L V P E L F M T D F P A R L F L E N S K L E H S E D E G S V L G Q G G S G T V I Y R A R Y Q G Q P V A V K R F H I K K F K N F A N V P A D T M L R H L R A T D A M K N F S E F R Q E A S M L H A L Q H P C I V A L I G I S I H P L C F A L E L A P L S S L N T V L S E N A R D S S F I P L G H M L T Q K I A Y Q I A S G L A Y L H K K N I I F C D L K S D N I L V W S L D V K E H I N I K L S D Y G I S R Q S F H E G A L G V E G T P G Y Q A P E I R P R I V Y D E K V D M F S Y G M V L Y E L L S G Q R P A L G H H Q L Q I A K K L S K G I R P V L G Q P E E V Q F R R L Q A L M M E C W D T K P E K R P L A L S V V S Q M K D P T F A T F M Y E L C C G K Q T A F F S S Q G Q E Y T V V F W D G K E E S R N Y T V V N T E K G L M E V Q R M C C P G M K V S C Q L Q V Q R S L W T A T E D Q K I Y I Y T L K G M C P L N T P Q Q A L D T P A V V T C F L A V P V I K K N S Y L V L A G L A D G L V A V F P V V R G T P K D S C S Y L C S H T A N R S K F S I A D E D A R Q N P Y P V K A M E V V N S G S E V W Y S N G P G L L V I D C A S L E I C R R L E P Y M A P S M V T S V V C S S E G R G E E V V W C L D D K A N S L V M Y H S T T Y Q L C A R Y F C G V P S P L R D M F P V R P L D T E P P A A S H T A N P K V P E G D S I A D V S I M Y S E E L G T Q I L I H Q E S L T D Y C S M S S Y S S S P P R Q A A R S P S S L P S S P A S S S S V P F S T D C E D S D M L H T P G A A S D R S E H D L T P M D G E T F S Q H L Q A V K I L A V R D L I W V P R R G G D V I V I G L E K D S G A Q R G R V I A V L K A R E L T P H G V L V D A A V V A K D T V V C T F E N E N T E W C L A V W R G W G A R E F D I F Y Q S Y E E L G R L E A C T R K R R
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:16243488}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000269|PubMed:16243488};
Active site	ACT_SITE 1386 1386 Proton acceptor. {ECO:0000255|PROSITE-ProRule:PRU00159}.
Pfam	PF12796 PF16095 PF00069
InterPro	IPR002110 IPR020683 IPR036770 IPR032171 IPR011009 IPR001611 IPR003591 IPR032675 IPR027417 IPR000719 IPR020859 IPR036322