Uniprot ID	Q42675
Uniprot Name	TKTA_CRAPL
Taxonomy ID	4153
Sequence	M A K T T P S S P S A A A A A E L V V K S V N T I R F L A I D A V E N V K S G H P G M P M G C A P M G H V L F D E F M K F N P K N P Y W F N R D R F V L S A G H G A M L L Y G L L H L A G Y D S V K V E D L K G L R Q W G S K T P A H P E N F E T P G V E V T T G P L G Q G V G S A V G L A L A E K H L G A R Y N K P D F E M V D H Y T Y M I L G D G C Q M E G I S N E A S S L A A H W G L G K L I A L Y D D N H I T I D G D T D L A F T E D V G K R F E A L G W H V L T V A N G N D G Y D E I R E A I K V A K S V T D K P T L I K V A T T I G F G S P N K A N T Y G V H G N A L G P K E A E A T R Q N L G W P Y E T F H V P D D V K K H W S R H I S E G A E L E S A W N A K F A E Y E K K Y P K E A A E L K S I I T G E L P L G W E K A L P T Y T P E S P G N P T R T L S H Q N L N A V A A V L P G L I G G S A D L T A S N M A F L K S S G D F Q K E T P T G R N L K F G A R E H G M G A I C N G V A L H S P G L V P F S A T Y F V F T D Y M R A A I R I A A L S K A R V V Y I M T H D S I G L G E D G P T H Q P V E H L A S F R A M P N I L V L R P A D G N E T A G A Y K V A V E N A G R P S I L S L S R Q K L P Q L P G T S V E G V G R G G Y V I S D N S K D G E K P E V I L M G T G S E L E I A A R A G E E L R K E G K K V R V V S L V S W E L F G E Q S K E Y K E M V L P S E V T A R V S V E A G S T F G W E R F V G L K G R A V G I D R F G A S A S A E R L Y K E F G I T V E A V V A A A K E L C
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000250}; Note=Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+). {ECO:0000250}; COFACTOR: Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937; Evidence={ECO:0000250}; Note=Binds 1 thiamine pyrophosphate per subunit. {ECO:0000250};
Active site	ACT_SITE 425 425 Proton donor. {ECO:0000250}.
Pfam	PF02779 PF02780 PF00456
InterPro	IPR029061 IPR009014 IPR005475 IPR005478 IPR020826 IPR033248 IPR033247 IPR005474