Uniprot ID	Q42676
Uniprot Name	TKTC_CRAPL
Taxonomy ID	4153
Sequence	V D H Y T Y C I L G D G C Q M E G V S N E A C S I A A H W G L G K L I A L Y D D N H I S I D G D T D I A F T E D V D K R F E A L G W H V I W V K N G N N G Y D K I R A A I K E A Q A V K D K P T M I K I T T T I G F G S P N K S N S Y S V H G S A L G A K E V E A T R Q N L G W P Y E P F H V P D D V K K H W S R H T P Q G A S L E S E W N A K F A E Y E K K Y P E E A A E L K S I I T G E L P L G W E K A L P T Y T P E N P G D A T R N L S Q Q N L N A L A K V L P G L L G G S A D L A S S N M T L L K S S G D F Q K N T P E E R N V R F G V R E H G M G A I C N G I A L H S P G L I P Y C A T F F V F T D Y M R A A M R I S A L C E A R V I Y V M T H D S I G L G E D G P T H Q P I E H L A S F R A M P N I L M L R P A D G N E T A G A Y K V A V Q N L K R P S V L A L S R Q K L P Q L P G T S I E G V E K G G Y V I S D N S S G N K P D V I L I G T G S E L E I A A K A G E V L R K E G K G V R V V S F V S W E L F D E Q S K E Y K E S V L P S S V T A R V S I E A G S T F G W G K I V G S K G K A I G I D R F G A S A P A G K I Y E E F G I T V E A V V A A A K E L I
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000250}; Note=Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+). {ECO:0000250}; COFACTOR: Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937; Evidence={ECO:0000250}; Note=Binds 1 thiamine pyrophosphate per subunit. {ECO:0000250};
Active site	ACT_SITE 266 266 Proton donor. {ECO:0000250}.
Pfam	PF02779 PF02780 PF00456
InterPro	IPR029061 IPR009014 IPR005475 IPR005478 IPR020826 IPR033248 IPR033247 IPR005474