Uniprot ID	Q53VY2
Uniprot Name	CAS3_THET8
Taxonomy ID	300852
Sequence	M S V E E A A L A L W A K S G N P F H P L L A H M L D T A A V A L A V L R M E P P R T R A L Y A E D W G L P E E G A L A W A A A L V G L H D L G K A S P V F Q A G W E E G K E R V Q R A G L P F G E L L D W V A H G V F T E L F L R R L L K E K G L P E R A A N D L A A A L G A H H G F P A N A E E K S R A R R H L R T E D P L W K E A R R W L L E E V F R R L G A P L P P S Q G N G E A R P E A V L R V M A L A S F A D W V A S D P S L F P Y G R D P R R G D Y L K E A L R L A Q E A L N R L G W P A F A K A Q R R E F G E L F P Y I P K P N A L Q E S V P A L L E G A C T P V L L L V E A P M G M G K T E A A L Y A H H L L Q A G L G H R G L Y V A L P T Q A T A N G L F P R V R G F L E R L G E G S R L E L Q L Q H G T A L L N P H Y A G L L E R A A P R Q V G E E E E G G A V A S A W F S A R K R A M L A P Y G V G T L D Q A L L G V L R V K H H F V R L W G L M N R V V V L D E V H A Y D V Y T S G L L Q A L L R W L R A L G S S A V V M T A T L P P S R R R A L L E A W A G E E V E G Q D L G P Y P R V V L V G E G V K A R S L P P A R E V E V A L E V L R E V D V E P L A Q R L K G A L P G A V G A I V N T V D R A Q D L Y R A L G E G T P L T L E E L A R R L G G I S G G Q A W E E V R Q A L P E R G G E V V G K V L T D G T L V F L L H A R F P A E E R A L R G S V V L A L F G K G G P R P P R A I L V A T Q V A E Q S L D L D F D L L Y T D L A P I D L L F Q R S G R L H R H E R P R P E E H A R P R L L L G V P E D L D F G K P L Y W D K V Y E D Y V L L A T W R A L S G R D R L R V P G D L E A L L E E I Y E G E N P E S F P E G L R E R A K K S L K A L Q E R R D R E A N T A R R L S L S E L D R L L A Y W D E G A L V A Q E R L E D D E E K A E T Q R L L T R L G D P S V A V V P L F R V G E G L F L D R E G R R R A P L K G E V S R E E A E A L F R R A V R L S R F P L P Q E L L K E E P P P A W R K S G L L R G L R P L E V G R V F R S G E R A F Q V E L D P E L G V V Y L P V
Cofactor	COFACTOR: Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000269|PubMed:21775431}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000269|PubMed:21775431}; Name=Ni(2+); Xref=ChEBI:CHEBI:49786; Evidence={ECO:0000269|PubMed:21775431}; Name=Cu(2+); Xref=ChEBI:CHEBI:29036; Evidence={ECO:0000269|PubMed:21775431}; Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000269|PubMed:21775431}; Note=The ssDNA endonuclease activity (residues 6-260) is stimulated by Mn(2+), Co(2+), Ni(2+), Cu(2+) and Zn(2+), but not by Mg(2+) or Ca(2+). A Ni(2+) ion is seen in crystals upon soaking. {ECO:0000269|PubMed:21775431};
Active site	No current data
Pfam	PF18395 PF18019
InterPro	IPR035011 IPR041372 IPR006483 IPR038257 IPR014001 IPR006474 IPR027417