Uniprot ID	Q5S006
Uniprot Name	LRRK2_MOUSE
Taxonomy ID	10090
Sequence	M A S G A C Q G C E E E E E E E A L K K L I V R L N N V Q E G K Q I E T L L Q L L E D M L V F T Y S D R A S K L F E D K N F H V P L L I V L D S Y M R V A S V Q Q A G W S L L C K L I E V C P G T L Q S L I G P Q D I G N D W E V L G I H R L I L K M L T V H H A N V N L S I V G L K A L D L L L D S G K L T L L I L D E E C D I F L L I F D A M H R Y S A N D E V Q K L G C K A L H V L F E R V S E E Q L T E F V E N K D Y T I L L S T F G S F R R D K E I V Y H V L C C L H S L A V T C S N V E V L M S G N V R C Y N L V V E A M K A F P T N E N I Q E V S C S L F Q K L T L G N F F N I L V L N E V H V F V V K A V R Q Y P E N A A L Q I S A L S C L A L L T E T I F L N Q D L E E R S E T Q E Q S E E E D S E K L F W L E P C Y K A L V R H R K D K H V Q E A A C W A L N N L L M Y Q N S L H E K I G D E D G Q F P A H R E V M L S M L M H S S S K D V F Q A A A H A L S T L L E Q N V N F R K I L L A K G V Y L N V L E L M Q K H A H A P E V A E S G C K M L S H L F E G S N P S L D T M A A V V P K I L T V M K A H G T S L S V Q L E A L R A I L H F V V P G L L E E S R E D S Q C R P N V L R K Q C F R T D I H K L V L V A L N R F I G N P G I Q K C G L K V I S S L A H L P D A T E T L S L Q G A V D S V L H T L Q M Y P D D Q E I Q C L G L H L M G C L M T K K N F C I G T G H L L A K I L A S T L Q R F K D V A E V Q T T G L Q T T L S I L E L S V S F S K L L V H Y S F D V V I F H Q M S S S V V E Q K D E Q F L N L C C K C F A K V A V D D E L K N T M L E R A C D Q N N S I M V E C L L L L G A D A N Q V K G A T S L I Y Q V C E K E S S P K L V E L L L N G G C R E Q D V R K A L T V S I Q K G D S Q V I S L L L R K L A L D L A N N S I C L G G F G I G K I D P S W L G P L F P D K S S N L R K Q T N T G S V L A R K V L R Y Q M R N T L Q E G V A S G S D G K F S E D A L A K F G E W T F I P D S S M D S V F G Q S D D L D S E G S E S S F L V K R K S N S I S V G E V Y R D L A L Q R C S P N A Q R H S N S L G P V F D H E D L L R R K R K I L S S D E S L R S S R L P S H M R Q S D S S S S L A S E R E H I T S L D L S A N E L K D I D A L S Q K C C L S S H L E H L T K L E L H Q N S L T S F P Q Q L C E T L K C L I H L D L H S N K F T S F P S F V L K M P R I T N L D A S R N D I G P T V V L D P A M K C P S L K Q L N L S Y N Q L S S I P E N L A Q V V E K L E Q L L L E G N K I S G I C S P L S L K E L K I L N L S K N H I P S L P G D F L E A C S K V E S F S A R M N F L A A M P A L P S S I T S L K L S Q N S F T C I P E A I F S L P H L R S L D M S H N N I E C L P G P A H W K S L N L R E L I F S K N Q I S T L D F S E N P H V W S R V E K L H L S H N K L K E I P P E I G C L E N L T S L D V S Y N L E L R S F P N E M G K L S K I W D L P L D G L H L N F D F K H V G C K A K D I I R F L Q Q R L K K A V P Y N R M K L M I V G N T G S G K T T L L Q Q L M K M K K P E L G M Q G A T V G I D V R D W S I Q I R G K R R K D L V L N V W D F A G R E E F Y S T H P H F M T Q R A L Y L A V Y D L S K G Q A E V D A M K P W L F N I K A R A S S S P V I L V G T H L D V S D E K Q R K A C I S K I T K E L L N K R G F P T I R D Y H F V N A T E E S D A L A K L R K T I I N E S L N F K I R D Q P V V G Q L I P D C Y V E L E K I I L S E R K A V P T E F P V I N R K H L L Q L V N E H Q L Q L D E N E L P H A V H F L N E S G V L L H F Q D P A L Q L S D L Y F V E P K W L C K V M A Q I L T V K V D G C L K H P K G I I S R R D V E K F L S K K K R F P K N Y M M Q Y F K L L E K F Q I A L P I G E E Y L L V P S S L S D H R P V I E L P H C E N S E I I I R L Y E M P Y F P M G F W S R L I N R L L E I S P F M L S G R E R A L R P N R M Y W R Q G I Y L N W S P E A Y C L V G S E V L D N R P E S F L K I T V P S C R K G C I L L G R V V D H I D S L M E E W F P G L L E I D I C G E G E T L L K K W A L Y S F N D G E E H Q K I L L D E L M K K A E E G D L L I N P D Q P R L T I P I S Q I A P D L I L A D L P R N I M L N N D E L E F E E A P E F L L G D G S F G S V Y R A A Y E G E E V A V K I F N K H T S L R L L R Q E L V V L C H L H H P S L I S L L A A G I R P R M L V M E L A S K G S L D R L L Q Q D K A S L T R T L Q H R I A L H V A D G L R Y L H S A M I I Y R D L K P H N V L L F T L Y P N A A I I A K I A D Y G I A Q Y C C R M G I K T S E G T P G F R A P E V A R G N V I Y N Q Q A D V Y S F G L L L H D I W T T G S R I M E G L R F P N E F D E L A I Q G K L P D P V K E Y G C A P W P M V E K L I T K C L K E N P Q E R P T S A Q V F D I L N S A E L I C L M R H I L I P K N I I V E C M V A T N L N S K S A T L W L G C G N T E K G Q L S L F D L N T E R Y S Y E E V A D S R I L C L A L V H L A A E K E S W V V C G T Q S G A L L V I N V E E E T K R H T L E K M T D S V T C L H C N S L A K Q S K Q S N F L L V G T A D G N L M I F E D K A V K C K G A A P L K T L H I G D V S T P L M C L S E S L N S S E R H I T W G G C G T K V F S F S N D F T I Q K L I E T K T N Q L F S Y A A F S D S N I I A L A V D T A L Y I A K K N S P V V E V W D K K T E K L C E L I D C V H F L K E V M V K L N K E S K H Q L S Y S G R V K A L C L Q K N T A L W I G T G G G H I L L L D L S T R R V I R T I H N F C D S V R A M A T A Q L G S L K N V M L V L G Y K R K S T E G I Q E Q K E I Q S C L S I W D L N L P H E V Q N L E K H I E V R T E L A D K M R K T S V E
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250|UniProtKB:Q5S007};
Active site	ACT_SITE 1994 1994 Proton acceptor. {ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10027}.
Pfam	PF16095 PF13855 PF00069
InterPro	IPR036770 IPR011989 IPR016024 IPR032171 IPR011009 IPR001611 IPR003591 IPR032675 IPR027417 IPR000719 IPR017441 IPR020859 IPR008271 IPR005225 IPR015943 IPR036322