Uniprot ID	Q6GH64
Uniprot Name	TKT_STAAR
Taxonomy ID	282458
Sequence	M F N E K D Q L A V D T L R A L S I D T I E K A N S G H P G L P M G A A P M A Y T L W T R H L N F N P Q S K D Y F N R D R F V L S A G H G S A L L Y S L L H V S G S L E L E E L K Q F R Q W G S K T P G H P E Y R H T D G V E V T T G P L G Q G F S M S V G L A L A E D H L A G K F N K E G Y N V V D H Y T Y V L A S D G D L M E G I S H E A A S F A G H N K L S K L V V L Y D S N D I S L D G E L N K A F S E N T K A R F E A Y G W N Y L L V K D G N D L E E I D K A I T T A K S Q E G P T I I E V K T T I G F G S P N K A G T N G V H G A P L G E D E R K L T F E N Y G L D P E K R F N V S E E V Y E I F Q N T M L K R A N E D E S Q W N S L L E K Y A E T Y P E L A E E F K L A I S G K L P K N Y K D E L P R F E F G H N G A S R A D S G T V I Q A I S K T V P S F F G G S A D L A G S N K S N V N D A T D Y S S E T P E G K N V W F G V R E F A M G A A V N G M A A H G G L H P Y G A T F F V F S D Y L K P A L R L S S I M G L N A T F I F T H D S I A V G E D G P T H E P I E Q L A G L R A I P N M N V I R P A D G N E T R V A W E V A L E S E S T P T S L V L T R Q N L P V L D V P E D V V E E G V R K G A Y T V Y G S E E T P E F L L L A S G S E V S L A V E A A K D L E K Q G K S V R V V S M P N W N A F E Q Q S E E Y K E S V I P S S V T K R V A I E M A S P L G W H K Y V G T A G K V I A I D G F G A S A P G D L V V E K Y G F T K E N I L N Q V M S L
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000250}; Note=Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+). {ECO:0000250}; COFACTOR: Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937; Evidence={ECO:0000250}; Note=Binds 1 thiamine pyrophosphate per subunit. {ECO:0000250};
Active site	ACT_SITE 410 410 Proton donor. {ECO:0000250}.
Pfam	PF02779 PF02780 PF00456
InterPro	IPR029061 IPR009014 IPR005475 IPR005478 IPR020826 IPR033248 IPR033247 IPR005474