Uniprot ID	Q6IM78
Uniprot Name	TOP1M_RAT
Taxonomy ID	10116
Sequence	M L L L W L R A L C R R F Q H V P R R V P S R Q V S R G S K A S R A G W G E T S K S S V K W K Q L E H K G P C F A P A Y E P L P D G V R F F Y D G K P V R L S L A A E E V A T F Y G K M L H L E C T T K E V F R R N F F S D W Q K E M T A E E R K L I T H L D K C D F S E I H R H F M E R A E A R R T L P R E Q K Q K L K E E A E K L Q Q E F G Y C I L D G H R E K I G N F K T E P P G L F R G R G D H P K M G M L K R R V M P E D V V I N C S R D S K I P E P P A G H Q W K E V R S D N T V M W L A A W V E N I Q N S F K Y I I L N P S S K P K G E M D W Q K Y E V A R R L K G V V D K I R A Q Y Q A D W K S P E M K K R Q L A V A L Y F I D K L A L R T G N E K E E G E T A D T V G C C S L R V E H V R L H T P A D G Q E H V V E L D F L G K D S I R Y K N H V T V E K L V F Q N L Q H F M E D K D P R D D L F D A L T T S S L N K H L Q D L M E G L T A K V F R T Y N A S I T L Q E Q L R V L T R A E D S L T C K V L A Y N R A N R A V A V L C N H Q R A I P K T F E E S M Q T L Q K K I E T K K A Q V A E A Q V E L Q K A E T D L R M R G D S K S K S F L Q K Q Q R L L K L E E Q L A R L C T K A T D K E E N K Q V A L G T A K L N Y L D P R I S I A W C K R F G V P V E K I Y N K T Q R E R F A W A F N Q A G E D F E F
Cofactor	COFACTOR: Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Divalent metal ions (calcium or magnesium). {ECO:0000250};
Active site	ACT_SITE 551 551 O-(3'-phospho-DNA)-tyrosine intermediate. {ECO:0000250}.
Pfam	PF14370 PF01028 PF02919
InterPro	IPR011010 IPR013034 IPR013030 IPR001631 IPR025834 IPR014711 IPR014727 IPR013500 IPR008336 IPR036202 IPR013499