Uniprot ID	Q6NKI3
Uniprot Name	CAS9_CORDI
Taxonomy ID	257309
Sequence	M K Y H V G I D V G T F S V G L A A I E V D D A G M P I K T L S L V S H I H D S G L D P D E I K S A V T R L A S S G I A R R T R R L Y R R K R R R L Q Q L D K F I Q R Q G W P V I E L E D Y S D P L Y P W K V R A E L A A S Y I A D E K E R G E K L S V A L R H I A R H R G W R N P Y A K V S S L Y L P D G P S D A F K A I R E E I K R A S G Q P V P E T A T V G Q M V T L C E L G T L K L R G E G G V L S A R L Q Q S D Y A R E I Q E I C R M Q E I G Q E L Y R K I I D V V F A A E S P K G S A S S R V G K D P L Q P G K N R A L K A S D A F Q R Y R I A A L I G N L R V R V D G E K R I L S V E E K N L V F D H L V N L T P K K E P E W V T I A E I L G I D R G Q L I G T A T M T D D G E R A G A R P P T H D T N R S I V N S R I A P L V D W W K T A S A L E Q H A M V K A L S N A E V D D F D S P E G A K V Q A F F A D L D D D V H A K L D S L H L P V G R A A Y S E D T L V R L T R R M L S D G V D L Y T A R L Q E F G I E P S W T P P T P R I G E P V G N P A V D R V L K T V S R W L E S A T K T W G A P E R V I I E H V R E G F V T E K R A R E M D G D M R R R A A R N A K L F Q E M Q E K L N V Q G K P S R A D L W R Y Q S V Q R Q N C Q C A Y C G S P I T F S N S E M D H I V P R A G Q G S T N T R E N L V A V C H R C N Q S K G N T P F A I W A K N T S I E G V S V K E A V E R T R H W V T D T G M R S T D F K K F T K A V V E R F Q R A T M D E E I D A R S M E S V A W M A N E L R S R V A Q H F A S H G T T V R V Y R G S L T A E A R R A S G I S G K L K F F D G V G K S R L D R R H H A I D A A V I A F T S D Y V A E T L A V R S N L K Q S Q A H R Q E A P Q W R E F T G K D A E H R A A W R V W C Q K M E K L S A L L T E D L R D D R V V V M S N V R L R L G N G S A H K E T I G K L S K V K L S S Q L S V S D I D K A S S E A L W C A L T R E P G F D P K E G L P A N P E R H I R V N G T H V Y A G D N I G L F P V S A G S I A L R G G Y A E L G S S F H H A R V Y K I T S G K K P A F A M L R V Y T I D L L P Y R N Q D L F S V E L K P Q T M S M R Q A E K K L R D A L A T G N A E Y L G W L V V D D E L V V D T S K I A T D Q V K A V E A E L G T I R R W R V D G F F S P S K L R L R P L Q M S K E G I K K E S A P E L S K I I D R P G W L P A V N K L F S D G N V T V V R R D S L G R V R L E S T A H L P V T W K V Q
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250|UniProtKB:Q99ZW2}; Note=Endonuclease activity on target dsDNA requires Mg(2+). {ECO:0000250|UniProtKB:Q99ZW2};
Active site	ACT_SITE 8 8 For RuvC-like nuclease domain. {ECO:0000250|UniProtKB:Q99ZW2}.; ACT_SITE 573 573 Proton acceptor for HNH nuclease domain. {ECO:0000250|UniProtKB:Q99ZW2}.
Pfam	PF18470 PF17893 PF18525 PF17894 PF01844 PF18541
InterPro	IPR040619 IPR040796 IPR041217 IPR041225 IPR002711 IPR033114 IPR003615 IPR036397 IPR041383