Uniprot ID | Q81258 |
Uniprot Name | POLG_HCVNZ |
Taxonomy ID | 356415 |
Sequence |
M
S
T
L
P
K
P
Q
R
K
T
K
R
N
T
I
R
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T
S
F
G
N
T
I
T
C
Y
I
K
A
T
A
A
A
K
A
A
N
L
R
N
P
D
F
L
V
C
G
D
D
L
V
V
V
A
E
S
D
G
V
D
E
D
R
A
A
L
R
A
F
T
E
A
M
T
R
Y
S
A
P
P
G
D
A
P
Q
A
T
Y
D
L
E
L
I
T
S
C
S
S
N
V
S
V
A
R
D
D
K
G
R
R
Y
Y
Y
L
T
R
D
A
T
T
P
L
A
R
A
A
W
E
T
A
R
H
T
P
V
N
S
W
L
G
N
I
I
M
Y
A
P
T
I
W
V
R
M
V
M
M
T
H
F
F
S
I
L
Q
S
Q
E
I
L
D
R
P
L
D
F
E
M
Y
G
A
T
Y
S
V
T
P
L
D
L
P
A
I
I
E
R
L
H
G
L
S
A
F
T
L
H
S
Y
S
P
V
E
L
N
R
V
A
G
T
L
R
K
L
G
C
P
P
L
R
A
W
R
H
R
A
R
A
V
R
A
K
L
I
A
Q
G
G
K
A
K
I
C
G
L
Y
L
F
N
W
A
V
R
T
K
T
N
L
T
P
L
P
A
A
G
Q
L
D
L
S
S
W
F
T
V
G
V
G
G
N
D
I
Y
H
S
V
S
R
A
R
T
R
H
L
L
L
C
L
L
L
L
T
V
G
V
G
I
F
L
L
P
A
R
|
Cofactor |
COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; Note=Binds 1 zinc ion per NS3 protease domain. {ECO:0000250}; COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; Note=Binds 1 zinc ion per NS5A N-terminal domain. {ECO:0000250}; |
Active site |
ACT_SITE 958 958 For protease NS2-3 activity; shared with dimeric partner. {ECO:0000255|PROSITE-ProRule:PRU01030}.; ACT_SITE 978 978 For protease NS2-3 activity; shared with dimeric partner. {ECO:0000255|PROSITE-ProRule:PRU01030}.; ACT_SITE 999 999 For protease NS2-3 activity; shared with dimeric partner. {ECO:0000255|PROSITE-ProRule:PRU01030}.; ACT_SITE 1089 1089 Charge relay system; for serine protease NS3 activity. {ECO:0000255|PROSITE-ProRule:PRU01166}.; ACT_SITE 1113 1113 Charge relay system; for serine protease NS3 activity. {ECO:0000255|PROSITE-ProRule:PRU01166}.; ACT_SITE 1171 1171 Charge relay system; for serine protease NS3 activity. {ECO:0000255|PROSITE-ProRule:PRU01166}. |
Pfam |
PF07652
PF01543
PF01542
PF01539
PF01560
PF01538
PF01006
PF01001
PF01506
PF08300
PF08301
PF12941
PF02907
PF00998
|
InterPro |
IPR011492
IPR002521
IPR002522
IPR002519
IPR002531
IPR002518
IPR042205
IPR042209
IPR000745
IPR001490
IPR002868
IPR013193
IPR038568
IPR024350
IPR014001
IPR001650
IPR013192
IPR038170
IPR027417
IPR009003
IPR004109
IPR007094
IPR002166
|