Uniprot ID	Q8BXA7
Uniprot Name	PHLP2_MOUSE
Taxonomy ID	10090
Sequence	M K H N G S R T C L N R R S R F G S R E R D W L R E D V K R G C V Y L Y G A D T T T A T T T T S S S S S S S S S S D L H L V L C T V E T P A S E I C A G E G R E S L Y L Q L H G D L V R R L E P S E R P L Q I V Y D Y L S R L G F E D P V R I Q E E A T N P D L S C M I R F Y G E K P C Q M D H L D R I L L S G I Y N V R K G K T Q L H K W A E R L V V L C G T C L I V S S V K D C Q T G K M H I L P L V G G K I E E V K R R Q H S L A F S S A G A Q A Q T Y H V S F E T L A E Y Q R W Q R Q A S K V V S Q R M S T V D L S C Y S L E E V P E H L F Y S Q D I T Y L N L R H N F M Q L E R P G G L D T L H K F S Q L K G L N L S H N K L G L F P V L L C E I S T L T E L S L S C N G F H D L P S Q I G K L L N L Q T L S L D G N G L T A L P D E L G N L R Q L T S L G I S F N D F R H I P E V L E K L T M L D K V A M A G N R L E V L N L G A L T R M S Q V K H V D L R M N H L K T V I T E N M E G N K H I T H M D L R D N Q L T D L D L S S L C S L E Q L H C E R N Q L R E L T L S G F S L R T L Y A S W N R L T A V N V Y P V P S L L T S L E L S Q N L L E C V P D W A C E A K K L E I L D I S H N L L T E V P M R I L S S L S L R K L M V G H N H I H V L P A L V E H I P L E V L D I Q H N T L S R L P D T L F S K A L N L R Y L N A S A N S L E S L P S A C A G E E S L S V L Q L L Y L T S N L L T D Q C I P V L V G H P H L R V L H L A N N Q L Q T F P A S K L N K L E Q L E E L N L S G N K L T A I P T T I A N C K R L H T L V A H A N N I S I F P E I L Q L P Q I Q F V D L S C N D L T E I L I P E A L P A T L Q D L D L T G N T N L V L E H K T L D M F S H I T A L K I D Q K P L P A T D S A V T S T F W S H G L A E M A G Q R N K L C V S A L A M D N F A E G V G A V Y G M F D G D R N E E L P R L L Q C T M A D V L L E E V Q H S T N D T V F M T N T F L V S H R K L G M A G Q K L G S S A L L C Y I R P D T A D P T S S F S L T V A N V G M C Q A V L C R G G K P V P L S K V F S L E H D P E E A Q R V K D Q K A I I T E D N K V N G V T C C T R L L G C T Y L Y P W I L P K P H I A S T P L T I Q D E L L I L G N K A L W E H L S Y L E A V N A V R H V Q D P L A A A K K L C T L A Q S Y G C Q D N V G A M V V Y L N I G E E G C T C E M N G L T L P G P V G F A S T A A L K D T P K P T T P S S S S G I A S E F S S E M S T S E V S S E V G S T A S D E H N T V G L E A S L L P R P E R R C S L H P A S S A G V F Q R Q P S C A T F S S N Q S D N G L D S D D D Q P V E G V I T N G S R V E V E V D I H C C R G R E P E S S P P L P K N S S N A C S E E R A R G A G F G I R R Q N S V N S G I L L P A N R D K M E L Q K S P S T S C L Y G K K L S N G S I V P L E D S L N L I E V A T E A P K R K T G Y F A A P T Q L E P E D Q F V V P R D L E E E V K E Q M K Q H Q E G R P E P E P R G E E R T E P L E E F D T A L
Cofactor	COFACTOR: Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Note=Binds 2 manganese ions per subunit. Mn(2+) is inhibitory below pH 8 and activating above pH 8 (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:Q6ZVD8};
Active site	No current data
Pfam	PF13855 PF00481
InterPro	IPR001611 IPR003591 IPR032675 IPR011993 IPR036457 IPR001932