Uniprot ID	Q8J294
Uniprot Name	ARO1_THACU
Taxonomy ID	107832
Sequence	M A T A S V E Q P D L T K V S I L G K D S I H C G F H L S P Y I A D T V L T N L P A S T Y V L I T D T R V A K F H L E S F E A A F T D A L A A R P N T S A R F L T H V I P P G E T S K S R E G K A E I E D F L L D N S C T R D T V V L A L G G G V I G D L V G F V A A T F M R G V R F V Q I P T T L L A M V D S S V G G K T A I D T P H G K N L I G S F W Q P S Y V F I D A A F L E T L P Q R E F V N G M A E V I K T A A I W N E D E F S M L E A S A P A L F A A I G S S S S T T S A G R T T A T R S E A Q S L L L H V I T E S I G V K A H I V T L D E R E T G L R N L V N F G H T I G H A I E A V L T P T I L H G E C V A I G M V L E G E V A R Q L G V L S Q V G V G R I T R A L K A Y G L P T S T K D P R I A A V P A S R L L T I D R L L D I M K I D K K N S G P E K K I V L L S R I G K T Y E E R A T G V K D E V I R R V L A E A C R V I P G I P R G N P V R M S T P G S K S I S N R A L V L A A L G N G T C R L R N L L H S D D T Q V M M S A L I E L K G A K F A W E D G G E T L V V S G G G G A F T I P P A G K E L Y L G N A G T A A R F L T T V C T L V G P D S S S A T A S S E F P E G Y T F I T G N A R M K Q R P C G P L V D A L R A N G S K V K Y I E S E G C L P L H I G A G G L K G G T I Q L A A S V S S Q Y V S S I L L C A P Y A R D E D V V L E L V G G Q V I S Q P Y I D M T L A M M K T F G V E V T R R K A E D G T L L D I Y D I P R A Q Y T N P E K Y A I E S D A S S A T Y P L A V A A I T G T T C T I E N I G T S S L Q G D A G F A V N V L K R M G C K V E Q S E N E T T V T G P P I G Q L K A I G L V D M E T M T D A F L T A V V V A A V C G E G S A E G L E S D V P K N T T R I L G I A N Q R V K E C N R I R A M I D E L A K F G V K T K E L D D G L E V Y G Q P I E T L N K N V S V H C Y D D H R V A M A F S V L A T V V P G T I L E E K R C V E K T W P N W W D D L T N K I G I D V E G I E L A H Q S P A V A K Y N P E A T I I I V G M R G A G K T H I G G I A A A S L G W K F I D A D H V F E G R T G E L V S Q Y V R S K G W T A F R Q A E S Q I I Q D L L A E N P T R T I I S T G G G I V E S P L N R A L L S G Y G R A T G P V V Y V M R D V N E I L S Y L G S E T A R P A Y G E E I A D V Y W R R E P W F R E V S T H E Y I S Y T G G F H A A N G A T P G E I A S A C R D E T A R F F R Q I T G I K P N L S E A L A Q G E R S F F L S L T Y P D L L P A V P S I P L L T A G A D A I E L R V D L L N P S G D P V T G P P N I P S L D F V A T Q L S A L R H T S S L P V V F T V R T A S Q G G A F P D T A E K E A F A L Y N L A L R H G V E Y I D V E I S W S D K K I Q D L A A R K G A S Q I I A S W H D W S G N M K W N G A V V K E K Y A L A E R V G D I V K I V G K A L S I E D N F A L R A F A A A H T S K P F I G I N M G A E G Q L S R V L N T A F T P V S H P L L P T R A A P G Q M S V Q D I H T A L H L N G Q L A P Q K F Y L F G S P I A H S M S P H L H N T G F E K L G L P H K Y H I F E T A T I T D E V K A V I R A P E F G G A S V T I P L K L D I I P L L D E V S P E A K A I G A V N T I I P R K R A D G S T S L F G T N T D W R A I H D L A R N N L V V G I T N E T T A L V L G A G G T A R A A L Y A I H A L G I K T I Y L F N R T R A A A Q A L A D T F P T F G I I P L D S L N S F P K A A P T V V V S A I P A T G T T T E K A S D S A G V Y L P P S L F E A P S G V V V E M A Y K P A V T P V L G L A A K S S G W V G V R G V D I L C E Q G F Y Q Y E A W T G R K A P R A A M K A K V I S L Y D S Q Q
Cofactor	COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 2 Zn(2+) ions per subunit.;
Active site	ACT_SITE 270 270 Proton acceptor; for 3-dehydroquinate synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 285 285 Proton acceptor; for 3-dehydroquinate synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 856 856 For EPSP synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 1224 1224 Proton acceptor; for 3-dehydroquinate dehydratase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 1252 1252 Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.
Pfam	PF01761 PF01487 PF00275 PF18317 PF01488 PF08501 PF01202
InterPro	IPR013785 IPR016037 IPR030960 IPR001381 IPR001986 IPR036968 IPR006264 IPR023193 IPR036291 IPR027417 IPR008289 IPR013792 IPR041121 IPR031322 IPR013708 IPR010110 IPR000623 IPR023000 IPR006151