Uniprot ID	Q8MLZ3
Uniprot Name	PDE5_DICDI
Taxonomy ID	44689
Sequence	M M F S K R K S I R F N P E G D Y T E L P R G G Y V V P S K L G G I Q F G V P P E T I K D S M A L K I D V P T I Y V F P E E L W D R K T G I N A A E A E F P A Y F N Y F I L K R K V S F V C T K E Q E Q R I R I V F Q E T L L G P P E F N T G I I I N S S S S T T D T S K T S P I K K Q T S S S S P P L S P Q Q Q Q P P P P L V K Q P S Q Q Q L E E L A T M D T C H Y H H H H H H Q E V N D N D N N N N T T T N N N N I E I L E Q Q Q Q Q Q Q Q Q Q Q Q Q D E D S T D V D E E F Q K E F S S T F P R S E I P N L E K E C K Y L R T F N S V D E L F D F I L F D D N G I A K L S D D V E I H F Q E D Q S L F K V L Q F E E T G K G N K V Q T L V A T I P S K I L F P D M I N S I S T I N D N K I F D P P T F G I T I I G S S H G F D P K K S T T G F V L W I N K R G I M V D P P L N S S S F L Q S Q G V P T R M V D H I I L T H C H A D H D S G T F Q K L L E E Y Q I T V V T T P T I L G S F L R K Y G A L S N L S T D L L R R L F I F R P V M I G E P M I I S G A E F R F F Y T I H T I P T I S F E V F Y G G K S I F Y S G D T C Y D P N R I K D M N K R G I M K T S R M K F F L R P W N H T V V L H E A G V P P I H T P V S V L R A L P D E V K N R L Y L V H I S E H T L P A G S G L K I A K E G V A H T L S L D V M K S S H S E A V D I L K L V E S V D I F R S I P L T Q A C E I L Q T A T K R K Y S Q G S V I I A R D T E P D A F Y V V A S G V V C V N I G E L K K N L I V G D Y F G E M S L V M G G L R S A N V Q A V T D V E V L S F N K E D F L S I T R N S T E S I Q F I T R L W E M R N E K S W E T M S L N S V F S R C T N S Q K T A I Q S I L V R E L I K K D E T L W C K G E E A L F G C L V A E G S F V F K E D D S L E S F S Q G S F L G D I N A M T T Q P P S I H K T T V V A K E E S V I Y K V L S Q D L I K F F S N N P G I Q L A F L D T I F V D A L R D Q V Q Q L V N S K L T Y
Cofactor	COFACTOR: Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000269|PubMed:12429831}; Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:12429831}; Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000269|PubMed:12429831}; Note=Divalent metal cation. Can use Mn(2+) or, to a lower extent, Mg(2+) or Zn(2+). Half-maximal activation occurs between 10 and 100 uM of Mn(2+) whereas maximal activation occurs with 10 mM of Zn(2+) or Mg(2+). {ECO:0000269|PubMed:12429831};
Active site	No current data
Pfam	PF00027 PF00753
InterPro	IPR018490 IPR018488 IPR000595 IPR001279 IPR036866 IPR014710