Uniprot ID	Q8X071
Uniprot Name	ARO1_NEUCR
Taxonomy ID	367110
Sequence	M A E P I S N P T R I N I L G K D N I I I D H G I W L N F V A Q D L L Q N I K S S T Y I L I T D T N L Y K T Y V P P F Q S V F E K A A P Q D V R L L T Y A I P P G E Y S K G R D T K A E I E D W M L S H Q C T R D T V I I A L G G G V I G D M I G Y V A A T F M R G V R F V Q C P T T L L A M V D S S I G G K T A I D V P M G K N L I G A F W Q P E R I Y I D L T F L N T L P V R E F I N G M A E V I K T A A I W D E N E F T A L E E N A K A I L E A V R S K N K S A D R L A P I R D I L K R I V L G S A R V K A E V V S S D E R E G G L R N L L N F G H S I G H A Y E A I L T P Q V L H G E A V A I G M V K E A E L A R F L G V L R P S A V A R L S K C I A S Y D L P T S L Q D K R I V K L T A G K E C P V D V L L Q K M A V D K K N E G R K K K I V L L S A I G K T Y E P K A S V V E D R A I R I V L S P C I R V F A G V P K D L N V S V T P P G S K S I S N R A L I L A A L G E G T T R I H N L L H S D D T Q V M L N A V A Q L Q G A S F S W E E G D V L V V K G N G G K L Q A T S T P L Y L G N A G T A S R F L T S V A A L C N P S D V N S T V L T G N A R M K Q R P I G A L V D A L R A N G V G V K Y L E K E H S L P V Q V D A A G G L A G G V M E L A A T I S S Q Y V S S L L M A A P Y A R E P V T L R L V G G K P I S Q P Y I D M T I A M M A S F G V Q V Q R S A E D P N T Y Y I P Q G T Y K N P E T Y V V E S D A S S A T Y P L A I A A I T G T T C T V P N I G S K S L Q G D A R F A I E V L R P M G C T V E Q T D V S T T V T G P P I G T L K A I P H V D M E P M T D A F L T A S V L A A V A S G T T Q I T G I A N Q R V K E C N R I L A M K D Q L A K F G V H C N E L E D G I E V I G I P Y T E L K N P T E G I Y C Y D D H R V A M S F S V L S T I S P H P V L I L E R E C T G K T W P G W W D T M S N Y F K V H L E G E E E P H S S H V S H E K P R K G N P K S I F I I G M R G A G K S T A G K W M S E V L N R P L I D L D H E L E R R E G Q T I P E I I R S E R G W E G F R K A E L E L L E D V I K N N P T G H I F S C G G G I V E T E A A R K M L L S Y S Q N G G I V L L V H R D T D Q V V E Y L M R D K S R P A Y S E N I R E V Y Y R R K P F F E E C S N F R Y Y S P H P D G S K A L T E P P F D F S Q F L S V I C G H S N H L E E V K K K P H S F F V S L T V P N V S K A L D I I P K V V V G S D A V E L R V D L L E D Y D P E F V A K Q V A L L R S A A R I P I V Y T V R T V S Q G G K F P D D D Y E L A L K L Y R T G L Q A G V E Y L D L E M T M P D E V I E A V T N E K G Y T H I I A S H H D P K A T L S W K N G G W I Q Y Y N K A L Q H G D V V K L V G V A R E L A D N F A L A R F K A S L A A A H D K P L I A L N M G A A G K L S R V L N G F L T P V S H P A L P S K A A P G Q L S A A E I R Q A L A L I G E L E P R S F H L F G N P I S A S R S P A L H N A L F R D N G L P H Q Y S L F E T D N A A D V K D L I R A P G F G G A S V T I P L K L D I M P L L D E V S D A A K V I G A V N T I I P V R N G D K V T L R G D N T D W M G M V Y A L R N A G V V K C T K E S P T A G M V V G A G G T T R A A V H A L H D L G F A P I Y V V A R N A D R V K A L A E S F P A E Y D I R S L S T P E E V A A E S T A Q P S V V I S T I P A D K P I D Q S M R E V I V A S L R H P S V A D G K H V L L E M A Y T P R H T P L M Q L A E D A H W Q T I P G L E V L A A Q G W Y Q F Q L W T G I T P I Y T D A Q A A V M G N
Cofactor	COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 2 Zn(2+) ions per subunit.;
Active site	ACT_SITE 258 258 Proton acceptor; for 3-dehydroquinate synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 273 273 Proton acceptor; for 3-dehydroquinate synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 816 816 For EPSP synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 1168 1168 Proton acceptor; for 3-dehydroquinate dehydratase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 1196 1196 Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.
Pfam	PF01761 PF01487 PF00275 PF01488 PF08501 PF01202
InterPro	IPR018508 IPR013785 IPR016037 IPR030960 IPR001381 IPR001986 IPR036968 IPR006264 IPR023193 IPR036291 IPR027417 IPR008289 IPR013792 IPR031322 IPR013708 IPR010110 IPR000623 IPR023000 IPR006151