Uniprot ID	Q92630
Uniprot Name	DYRK2_HUMAN
Taxonomy ID	9606
Sequence	M L T R K P S A A A P A A Y P T G R G G D S A V R Q L Q A S P G L G A G A T R S G V G T G P P S P I A L P P L R A S N A A A A A H T I G G S K H T M N D H L H V G S H A H G Q I Q V Q Q L F E D N S N K R T V L T T Q P N G L T T V G K T G L P V V P E R Q L D S I H R R Q G S S T S L K S M E G M G K V K A T P M T P E Q A M K Q Y M Q K L T A F E H H E I F S Y P E I Y F L G L N A K K R Q G M T G G P N N G G Y D D D Q G S Y V Q V P H D H V A Y R Y E V L K V I G K G S F G Q V V K A Y D H K V H Q H V A L K M V R N E K R F H R Q A A E E I R I L E H L R K Q D K D N T M N V I H M L E N F T F R N H I C M T F E L L S M N L Y E L I K K N K F Q G F S L P L V R K F A H S I L Q C L D A L H K N R I I H C D L K P E N I L L K Q Q G R S G I K V I D F G S S C Y E H Q R V Y T Y I Q S R F Y R A P E V I L G A R Y G M P I D M W S L G C I L A E L L T G Y P L L P G E D E G D Q L A C M I E L L G M P S Q K L L D A S K R A K N F V S S K G Y P R Y C T V T T L S D G S V V L N G G R S R R G K L R G P P E S R E W G N A L K G C D D P L F L D F L K Q C L E W D P A V R M T P G Q A L R H P W L R R R L P K P P T G E K T S V K R I T E S T G A I T S I S K L P P P S S S A S K L R T N L A Q M T D A N G N I Q Q R T V L P K L V S
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:9748265}; ; COFACTOR: Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000269|PubMed:9748265};
Active site	ACT_SITE 348 348 Proton acceptor. {ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10027}.
Pfam	PF00069
InterPro	IPR042521 IPR011009 IPR000719 IPR017441 IPR008271