Uniprot ID	Q9BYP7
Uniprot Name	WNK3_HUMAN
Taxonomy ID	9606
Sequence	M A T D S G D P A S T E D S E K P D G I S F E N R V P Q V A A T L T V E A R L K E K N S T F S A S G E T V E R K R F F R K S V E M T E D D K V A E S S P K D E R I K A A M N I P R V D K L P S N V L R G G Q E V K Y E Q C S K S T S E I S K D C F K E K N E K E M E E E A E M K A V A T S P S G R F L K F D I E L G R G A F K T V Y K G L D T E T W V E V A W C E L Q D R K L T K A E Q Q R F K E E A E M L K G L Q H P N I V R F Y D S W E S I L K G K K C I V L V T E L M T S G T L K T Y L K R F K V M K P K V L R S W C R Q I L K G L Q F L H T R T P P I I H R D L K C D N I F I T G P T G S V K I G D L G L A T L M R T S F A K S V I G T P E F M A P E M Y E E H Y D E S V D V Y A F G M C M L E M A T S E Y P Y S E C Q N A A Q I Y R K V T S G I K P A S F N K V T D P E V K E I I E G C I R Q N K S E R L S I R D L L N H A F F A E D T G L R V E L A E E D D C S N S S L A L R L W V E D P K K L K G K H K D N E A I E F S F N L E T D T P E E V A Y E M V K S G F F H E S D S K A V A K S I R D R V T P I K K T R E K K P A G C L E E R R D S Q C K S M G N V F P Q P Q N T T L P L A P A Q Q T G A E C E E T E V D Q H V R Q Q L L Q R K P Q Q H C S S V T G D N L S E A G A A S V I H S D T S S Q P S V A Y S S N Q T M G S Q M V S N I P Q A E V N V P G Q I Y S S Q Q L V G H Y Q Q V S G L Q K H S K L T Q P Q I L P L V Q G Q S T V L P V H V L G P T V V S Q P Q V S P L T V Q K V P Q I K P V S Q P V G A E Q Q A A L L K P D L V R S L N Q D V A T T K E N V S S P D N P S G N G K Q D R I K Q R R A S C P R P E K G T K F Q L T V L Q V S T S G D N M V E C Q L E T H N N K M V T F K F D V D G D A P E D I A D Y M V E D N F V L E S E K E K F V E E L R A I V G Q A Q E I L H V H F A T E R A T G V D S I T V D S N S S Q T G S S E Q V Q I N S T S T Q T S N E S A P Q S S P V G R W R F C I N Q T I R N R E T Q S P P S L Q H S M S A V P G R H P L P S P K N T S N K E I S R D T L L T I E N N P C H R A L F T S K S E H K D V V D G K I S E C A S V E T K Q P A I L Y Q V E D N R Q I M A P V T N S S S Y S T T S V R A V P A E C E G L T K Q A S I F I P V Y P C H Q T A S Q A D A L M S H P G E S T Q T S G N S L T T L A F D Q K P Q T L S V Q Q P A M D A E F I S Q E G E T T V N T E A S S P K T V I P T Q T P G L E P T T L Q P T T V L E S D G E R P P K L E F A D N R I K T L D E K L R N L L Y Q E H S I S S I Y P E S Q K D T Q S I D S P F S S S A E D T L S C P V T E V I A I S H C G I K D S P V Q S P N F Q Q T G S K L L S N V A A S Q P A N I S V F K R D L N V I T S V P S E L C L H E M S S D A S L P G D P E A Y P A A V S S G G A I H L Q T G G G Y F G L S F T C P S L K N P I S K K S W T R K L K S W A Y R L R Q S T S F F K R S K V R Q V E T E E M R S A I A P D P I P L T R E S T A D T R A L N R C K A M S G S F Q R G R F Q V I T I P Q Q Q S A K M T S F G I E H I S V F S E T N H S S E E A F I K T A K S Q L V E I E P A T Q N P K T S F S Y E K L Q A L Q E T C K E N K G V P K Q G D N F L S F S A A C E T D V S S V T P E K E F E E T S A T G S S M Q S G S E L L L K E R E I L T A G K Q P S S D S E F S A S L A G S G K S V A K T G P E S N Q C L P H H E E Q A Y A Q T Q S S L F Y S P S S P M S S D D E S E I E D E D L K V E L Q R L R E K H I Q E V V N L Q T Q Q N K E L Q E L Y E R L R S I K D S K T Q S T E I P L P P A S P R R P R S F K S K L R S R P Q S L T H V D N G I V A T G K S C L I N E L E N P L C V E S N A A S C Q Q S P A S K K G M F T D D L H K L V D D W T K E A V G N S L I K P S L N Q L K Q S Q H K L E T E N W N K V S E N T P S T M G Y T S T W I S S L S Q I R G A V P T S L P Q G L S L P S F P G P L S S Y G M P H V C Q Y N A V A G A G Y P V Q W V G I S G T T Q Q S V V I P A Q S G G P F Q P G M N M Q A F P T S S V Q N P A T I P P G P K
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250|UniProtKB:Q9H4A3};
Active site	ACT_SITE 294 294 Proton acceptor. {ECO:0000250|UniProtKB:Q9JIH7}.
Pfam	PF12202 PF00069
InterPro	IPR011009 IPR024678 IPR000719 IPR008271