Uniprot ID	Q9H4A3
Uniprot Name	WNK1_HUMAN
Taxonomy ID	9606
Sequence	M S G G A A E K Q S S T P G S L F L S P P A P A P K N G S S S D S S V G E K L G A A A A D A V T G R T E E Y R R R R H T M D K D S R G A A A T T T T T E H R F F R R S V I C D S N A T A L E L P G L P L S L P Q P S I P A A V P Q S A P P E P H R E E T V T A T A T S Q V A Q Q P P A A A A P G E Q A V A G P A P S T V P S S T S K D R P V S Q P S L V G S K E E P P P A R S G S G G G S A K E P Q E E R S Q Q Q D D I E E L E T K A V G M S N D G R F L K F D I E I G R G S F K T V Y K G L D T E T T V E V A W C E L Q D R K L T K S E R Q R F K E E A E M L K G L Q H P N I V R F Y D S W E S T V K G K K C I V L V T E L M T S G T L K T Y L K R F K V M K I K V L R S W C R Q I L K G L Q F L H T R T P P I I H R D L K C D N I F I T G P T G S V K I G D L G L A T L K R A S F A K S V I G T P E F M A P E M Y E E K Y D E S V D V Y A F G M C M L E M A T S E Y P Y S E C Q N A A Q I Y R R V T S G V K P A S F D K V A I P E V K E I I E G C I R Q N K D E R Y S I K D L L N H A F F Q E E T G V R V E L A E E D D G E K I A I K L W L R I E D I K K L K G K Y K D N E A I E F S F D L E R D V P E D V A Q E M V E S G Y V C E G D H K T M A K A I K D R V S L I K R K R E Q R Q L V R E E Q E K K K Q E E S S L K Q Q V E Q S S A S Q T G I K Q L P S A S T G I P T A S T T S A S V S T Q V E P E E P E A D Q H Q Q L Q Y Q Q P S I S V L S D G T V D S G Q G S S V F T E S R V S S Q Q T V S Y G S Q H E Q A H S T G T V P G H I P S T V Q A Q S Q P H G V Y P P S S V A Q G Q S Q G Q P S S S S L T G V S S S Q P I Q H P Q Q Q Q G I Q Q T A P P Q Q T V Q Y S L S Q T S T S S E A T T A Q P V S Q P Q A P Q V L P Q V S A G K Q L P V S Q P V P T I Q G E P Q I P V A T Q P S V V P V H S G A H F L P V G Q P L P T P L L P Q Y P V S Q I P I S T P H V S T A Q T G F S S L P I T M A A G I T Q P L L T L A S S A T T A A I P G V S T V V P S Q L P T L L Q P V T Q L P S Q V H P Q L L Q P A V Q S M G I P A N L G Q A A E V P L S S G D V L Y Q G F P P R L P P Q Y P G D S N I A P S S N V A S V C I H S T V L S P P M P T E V L A T P G Y F P T V V Q P Y V E S N L L V P M G G V G G Q V Q V S Q P G G S L A Q A P T T S S Q Q A V L E S T Q G V S Q V A P A E P V A V A Q T Q A T Q P T T L A S S V D S A H S D V A S G M S D G N E N V P S S S G R H E G R T T K R H Y R K S V R S R S R H E K T S R P K L R I L N V S N K G D R V V E C Q L E T H N R K M V T F K F D L D G D N P E E I A T I M V N N D F I L A I E R E S F V D Q V R E I I E K A D E M L S E D V S V E P E G D Q G L E S L Q G K D D Y G F S G S Q K L E G E F K Q P I P A S S M P Q Q I G I P T S S L T Q V V H S A G R R F I V S P V P E S R L R E S K V F P S E I T D T V A A S T A Q S P G M N L S H S A S S L S L Q Q A F S E L R R A Q M T E G P N T A P P N F S H T G P T F P V V P P F L S S I A G V P T T A A A T A P V P A T S S P P N D I S T S V I Q S E V T V P T E E G I A G V A T S T G V V T S G G L P I P P V S E S P V L S S V V S S I T I P A V V S I S T T S P S L Q V P T S T S E I V V S S T A L Y P S V T V S A T S A S A G G S T A T P G P K P P A V V S Q Q A A G S T T V G A T L T S V S T T T S F P S T A S Q L C I Q L S S S T S T P T L A E T V V V S A H S L D K T S H S S T T G L A F S L S A P S S S S S P G A G V S S Y I S Q P G G L H P L V I P S V I A S T P I L P Q A A G P T S T P L L P Q V P S I P P L V Q P V A N V P A V Q Q T L I H S Q P Q P A L L P N Q P H T H C P E V D S D T Q P K A P G I D D I K T L E E K L R S L F S E H S S S G A Q H A S V S L E T S L V I E S T V T P G I P T T A V A P S K L L T S T T S T C L P P T N L P L G T V A L P V T P V V T P G Q V S T P V S T T T S G V K P G T A P S K P P L T K A P V L P V G T E L P A G T L P S E Q L P P F P G P S L T Q S Q Q P L E D L D A Q L R R T L S P E M I T V T S A V G P V S M A A P T A I T E A G T Q P Q K G V S Q V K E G P V L A T S S G A G V F K M G R F Q V S V A A D G A Q K E G K N K S E D A K S V H F E S S T S E S S V L S S S S P E S T L V K P E P N G I T I P G I S S D V P E S A H K T T A S E A K S D T G Q P T K V G R F Q V T T T A N K V G R F S V S K T E D K I T D T K K E G P V A S P P F M D L E Q A V L P A V I P K K E K P E L S E P S H L N G P S S D P E A A F L S R D V D D G S G S P H S P H Q L S S K S L P S Q N L S Q S L S N S F N S S Y M S S D N E S D I E D E D L K L E L R R L R D K H L K E I Q D L Q S R Q K H E I E S L Y T K L G K V P P A V I I P P A A P L S G R R R R P T K S K G S K S S R S S S L G N K S P Q L S G N L S G Q S A A S V L H P Q Q T L H P P G N I P E S G Q N Q L L Q P L K P S P S S D N L Y S A F T S D G A I S V P S L S A P G Q G T S S T N T V G A T V N S Q A A Q A Q P P A M T S S R K G T F T D D L H K L V D N W A R D A M N L S G R R G S K G H M N Y E G P G M A R K F S A P G Q L C I S M T S N L G G S A P I S A A S A T S L G H F T K S M C P P Q Q Y G F P A T P F G A Q W S G T G G P A P Q P L G Q F Q P V G T A S L Q N F N I S N L Q K S I S N P P G S N L R T T
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:10660600};
Active site	ACT_SITE 368 368 Proton acceptor. {ECO:0000250|UniProtKB:Q9JIH7}.
Pfam	PF12202 PF00069
InterPro	IPR011009 IPR024678 IPR000719 IPR008271