Uniprot ID	Q9KUP2
Uniprot Name	TKT1_VIBCH
Taxonomy ID	243277
Sequence	M S S R K Q L A N A I R A L S M D G V Q K A N S G H P G A P M G M A D I A E V L W R S H L N H N P Q N P N W A D R D R F V L S N G H G S M L I Y S L L H L S G Y E L S I D D L K N F R Q L H S K T P G H P E Y G Y A P G I E T T T G P L G Q G I T N A V G M A I A E K A L A A Q F N K P G H D I V D H F T Y V F M G D G C L M E G I S H E A C S L A G T L G L G K L I A F W D D N G I S I D G H V E G W F S D D T P K R F E A Y G W H V I P A V D G H D A D A I N A A I E A A K A E T S R P T L I C T K T I I G F G S P N K A G S H D C H G A P L G N D E I K A A R E F L G W E H A P F E I P A D I Y A A W D A K Q A G A S K E A A W N E K F A A Y A K A Y P A E A A E Y K R R V A G E L P A N W E A A T S E I I A N L Q A N P A N I A S R K A S Q N A L E A F G K L L P E F M G G S A D L A P S N L T M W S G S K S L T A E D A S G N Y I H Y G V R E F G M T A I I N G I A L H G G F V P Y G A T F L M F M E Y A R N A M R M A A L M K V Q N I Q V Y T H D S I G L G E D G P T H Q P V E Q I A S L R M T P N M S T W R P C D Q V E S A V A W K L A I E R K D A P S A L I F S R Q N L A Q Q P R S A E Q V A N I A K G G Y I L K D C A G Q P E L I L I A T G S E V E L A V A A Y E Q L S A E G K A V R V V S M P S T D A F D K Q D A A Y R E A V L P A A V T K R I A I E A G I A D F W Y K Y V G F G G R I I G M T S F G E S A P A G E L F K L F G F T T E N V V K Q A K E L L A
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000250}; Note=Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+). {ECO:0000250}; COFACTOR: Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937; Evidence={ECO:0000250}; Note=Binds 1 thiamine pyrophosphate per subunit. {ECO:0000250};
Active site	ACT_SITE 412 412 Proton donor. {ECO:0000250}.
Pfam	PF02779 PF02780 PF00456
InterPro	IPR029061 IPR009014 IPR005475 IPR005478 IPR020826 IPR033248 IPR033247 IPR005474