Uniprot ID	Q9UBZ4
Uniprot Name	APEX2_HUMAN
Taxonomy ID	9606
Sequence	M L R V V S W N I N G I R R P L Q G V A N Q E P S N C A A V A V G R I L D E L D A D I V C L Q E T K V T R D A L T E P L A I V E G Y N S Y F S F S R N R S G Y S G V A T F C K D N A T P V A A E E G L S G L F A T Q N G D V G C Y G N M D E F T Q E E L R A L D S E G R A L L T Q H K I R T W E G K E K T L T L I N V Y C P H A D P G R P E R L V F K M R F Y R L L Q I R A E A L L A A G S H V I I L G D L N T A H R P I D H W D A V N L E C F E E D P G R K W M D S L L S N L G C Q S A S H V G P F I D S Y R C F Q P K Q E G A F T C W S A V T G A R H L N Y G S R L D Y V L G D R T L V I D T F Q A S F L L P E V M G S D H C P V G A V L S V S S V P A K Q C P P L C T R F L P E F A G T Q L K I L R F L V P L E Q S P V L E Q S T L Q H N N Q T R V Q T C Q N K A Q V R S T R P Q P S Q V G S S R G Q K N L K S Y F Q P S P S C P Q A S P D I E L P S L P L M S A L M T P K T P E E K A V A K V V K G Q A K T S E A K D E K E L R T S F W K S V L A G P L R T P L C G G H R E P C V M R T V K K P G P N L G R R F Y M C A R P R G P P T D P S S R C N F F L W S R P S
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Note=Probably binds two magnesium or manganese ions per subunit. {ECO:0000250};
Active site	ACT_SITE 156 156 {ECO:0000250}.; ACT_SITE 197 197 Proton donor/acceptor. {ECO:0000250}.
Pfam	PF03372 PF06839
InterPro	IPR004808 IPR020847 IPR036691 IPR005135 IPR010666