Uniprot ID	Q9UQ90
Uniprot Name	SPG7_HUMAN
Taxonomy ID	9606
Sequence	M A V L L L L L R A L R R G P G P G P R P L W G P G P A W S P G F P A R P G R G R P Y M A S R P P G D L A E A G G R A L Q S L Q L R L L T P T F E G I N G L L L K Q H L V Q N P V R L W Q L L G G T F Y F N T S R L K Q K N K E K D K S K G K A P E E D E E E R R R R E R D D Q M Y R E R L R T L L V I A V V M S L L N A L S T S G G S I S W N D F V H E M L A K G E V Q R V Q V V P E S D V V E V Y L H P G A V V F G R P R L A L M Y R M Q V A N I D K F E E K L R A A E D E L N I E A K D R I P V S Y K R T G F F G N A L Y S V G M T A V G L A I L W Y V F R L A G M T G R E G G F S A F N Q L K M A R F T I V D G K M G K G V S F K D V A G M H E A K L E V R E F V D Y L K S P E R F L Q L G A K V P K G A L L L G P P G C G K T L L A K A V A T E A Q V P F L A M A G P E F V E V I G G L G A A R V R S L F K E A R A R A P C I V Y I D E I D A V G K K R S T T M S G F S N T E E E Q T L N Q L L V E M D G M G T T D H V I V L A S T N R A D I L D G A L M R P G R L D R H V F I D L P T L Q E R R E I F E Q H L K S L K L T Q S S T F Y S Q R L A E L T P G F S G A D I A N I C N E A A L H A A R E G H T S V H T L N F E Y A V E R V L A G T A K K S K I L S K E E Q K V V A F H E S G H A L V G W M L E H T E A V M K V S I T P R T N A A L G F A Q M L P R D Q H L F T K E Q L F E R M C M A L G G R A S E A L S F N E V T S G A Q D D L R K V T R I A Y S M V K Q F G M A P G I G P I S F P E A Q E G L M G I G R R P F S Q G L Q Q M M D H E A R L L V A K A Y R H T E K V L Q D N L D K L Q A L A N A L L E K E V I N Y E D I E A L I G P P P H G P K K M I A P Q R W I D A Q R E K Q D L G E E E T E E T Q Q P P L G G E E P T W P K
Cofactor	COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250|UniProtKB:Q9WZ49}; Note=Binds 1 zinc ion per subunit. {ECO:0000250|UniProtKB:Q9WZ49};
Active site	ACT_SITE 575 575 {ECO:0000250|UniProtKB:Q9WZ49}.
Pfam	PF00004 PF17862 PF06480 PF01434
InterPro	IPR003593 IPR041569 IPR003959 IPR005936 IPR027417 IPR011546 IPR000642 IPR037219