Uniprot ID	Q9UYS8
Uniprot Name	TOP1_PYRAB
Taxonomy ID	272844
Sequence	M I L V I A E K P N V A R K I A G A L S E R R P I R K T I F G V P Y Y E V F R D G K K L I V A S A V G H L Y G L A P K Q D F F G Y P I F D I E W V P V Y I A E K N K D Y A K D Y I K A L S V L A K R V K E F I V A C D Y D T E G E V I G Y T A L K Y A C G V D P S R A K R M K F S A L T K R D L L N A W R N L E P T I N F G M A N A G I A R H V L D W Y W G V N L S R A L T H A I K R A S G K W V V L S T G R V Q G P T L K F L V E R E R E I Q S F V P K P Y W V I K L V I E K N G Q K L V A N Y E K D K I W S E E E A K K I V T E V K K S K A R V S N I E V K R Q K R N P P V P F D L G T L Q R E A Y S A F G F S P K K T L D I A Q S L Y E K G F T S Y P R T E S Q K L P K N L N F R L I I Q N I S R M P Q Y R P Y A H L L L G M P E L K P V E G K K E D P A H P A I Y P T G E I P G P G D L S K D E E K L Y D M I V R R F L A L F M E P A V R E S V K V T I L A G P H K F M L S G A R T V K Q G W L S V Y G K Y I K F D E V T L P E F F I G E R V R V L Q V R R E K K K T K P P A R Y S P A A V I K K M E D L G I G T K A T R A Q I L E T L Y Q R G Y I E G K K S I K V T P L G M K V I E T L E K Y V P E I I S V E L T R E F E R K M D L I M Q G K L T K E E V I E E A K V K L T K I L E E F K K R E L E I G L E L A R I V V G D V K D E I K E E K P I V V G K C P K C G G D L I V K Y N K K T G K R F V G C S N W P K C D V T Y P I L Q R G E I I P T N K T C C N G A P V V I I R D K G R D I E I C L D I K C K K W
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000255|HAMAP-Rule:MF_00952}; Note=Binds two Mg(2+) per subunit. {ECO:0000255|HAMAP-Rule:MF_00952};
Active site	ACT_SITE 317 317 O-(5'-phospho-DNA)-tyrosine intermediate. {ECO:0000255|HAMAP-Rule:MF_00952}.
Pfam	PF01131 PF01751 PF01396
InterPro	IPR000380 IPR003601 IPR023406 IPR013497 IPR013824 IPR013825 IPR013826 IPR023405 IPR003602 IPR013498 IPR005739 IPR028612 IPR006171 IPR034144