Uniprot ID	Q9W4T4
Uniprot Name	PDE4A_DROME
Taxonomy ID	7227
Sequence	M M R L A R F T Q G F S F N K N V A K H R G S G S S N G T G N G S G T G N G Q G L G G S C S A N G L A A T G G V G G G G G S G S G G G G C G S G S G S G S G K R K S K A R T K C F G G T V F R C C L P C R G G G S A A P A T S P P Q T P A Q T P D E L K V I P E D C N L E K S A E Q K R D L L E R N N K E D D L L N R T V S G S E L D L Y G G A G G G T K K H S L A D T I D T S V T T P I S L K T L I N D V D E E L D Q Q L S A A D I A A A S L A S G L V A R R A E P E T L S D A S V S P T A V V Q Q Q Q Q Q Q Q Q L Q Q P L L Q S Q P H F V P S S G N I L S Q V T L Y S G S N P S T N P C Q S A V Q N Q G Q N S N P N P N Q N P N T N P N Q N Q Q R C S C Q P Q T S P L P H I K E E E E S D Q A N F K H Q T S L K E H Q P L P P P I T I A T G Y C G S C E S V H H S S A T S S S A G T V P P G G Q Q T Q E Y I A G T S S T P S P R I K L K F R K P H K S C W S R I V L A P I G S A G G S S S A T T V I G S N S N E T L A S S S T T G G T A T T T Q N S S S V S V A A H H R L T S S S A S A L A T S H P S N S Q L L P T S K M Q A E Q G S I G D L Q K Y H S R Y L K N R R H T L A N V R F D V E N G Q G A R S P L E G G S P S A G L V L Q N L P Q R R E S F L Y R S D S D F E M S P K S M S R N S S I A S E R F K E Q E A S I L V D R S H G E D L I V T P F A Q I L A S L R S V R N N L L S L T N V P A S N K S R R P N Q S S S A S R S G N P P G A P L S Q G E E A Y T R L A T D T I E E L D W C L D Q L E T I Q T H R S V S D M A S L K F K R M L N K E L S H F S E S S R S G N Q I S E Y I C S T F L D K Q Q E F D L P S L R V E D N P E L V A A N A A A G Q Q S A G Q Y A R S R S P R G P P M S Q I S G V K R P L S H T N S F T G E R L P T F G V E T P R E N E L G T L L G E L D T W G I Q I F S I G E F S V N R P L T C V A Y T I F Q S R E L L T S L M I P P K T F L N F M S T L E D H Y V K D N P F H N S L H A A D V T Q S T N V L L N T P A L E G V F T P L E V G G A L F A A C I H D V D H P G L T N Q F L V N S S S E L A L M Y N D E S V L E N H H L A V A F K L L Q N Q G C D I F C N M Q K K Q R Q T L R K M V I D I V L S T D M S K H M S L L A D L K T M V E T K K V A G S G V L L L D N Y T D R I Q V L E N L V H C A D L S N P T K P L P L Y K R W V A L L M E E F F L Q G D K E R E S G M D I S P M C D R H N A T I E K S Q V G F I D Y I V H P L W E T W A D L V H P D A Q D I L D T L E E N R D Y Y Q S M I P P S P P P S G V D E N P Q E D R I R F Q V T L E E S D Q E N L A E L E E G D E S G G E S T T T G T T G T T A A S A L S G A G G G G G G G G G M A P R T G G C Q N Q P Q H G G M
Cofactor	COFACTOR: Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; Evidence={ECO:0000250}; Note=Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. {ECO:0000250};
Active site	ACT_SITE 871 871 Proton donor. {ECO:0000250}.
Pfam	PF18100 PF00233
InterPro	IPR003607 IPR040844 IPR023088 IPR002073 IPR036971 IPR023174