Uniprot ID	Q9WYP7
Uniprot Name	IOLO_THEMA
Taxonomy ID	243274
Sequence	M K L S L V I S T S D A A F D A L A F K G D L R K G M E L A K R V G Y Q A V E I A V R D P S I V D W N E V K I L S E E L N L P I C A I G T G Q A Y L A D G L S L T H P N D E I R K K A I E R V V K H T E V A G M F G A L V I I G L V R G R R E G R S Y E E T E E L F I E S M K R L L E L T E H A K F V I E P L N R Y E T D F I N T I D D A L R I L R K I N S N R V G I L A D T F H M N I E E V N I P E S L K R A G E K L Y H F H V A D S N R W A P G C G H F D F R S V F N T L K E I G Y N R Y V S V E C L P L P G G M E E A A E I A F K T L K E L I I K L T
Cofactor	COFACTOR: Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000269|PubMed:28258150}; Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:28258150}; Name=Ni(2+); Xref=ChEBI:CHEBI:49786; Evidence={ECO:0000269|PubMed:28258150}; Note=Binds 1 divalent metal cation per subunit. Mn(2+) is the most efficient metal cofactor, but can also use other divalent metal cations such as Ni(2+), Mg(2+), and, to a lesser extent, Co(2+) and Zn(2+), but not Ca(2+), Cu(2+), and Fe(2+). {ECO:0000269|PubMed:28258150};
Active site	ACT_SITE 149 149 Proton donor/acceptor. {ECO:0000305|PubMed:28258150}.; ACT_SITE 243 243 Proton donor/acceptor. {ECO:0000305|PubMed:28258150}.
Pfam	PF01261
InterPro	IPR036237 IPR013022