Uniprot ID	Q9ZGI4
Uniprot Name	PIKA2_STRVZ
Taxonomy ID	54571
Sequence	M S T V N E E K Y L D Y L R R A T A D L H E A R G R L R E L E A K A G E P V A I V G M A C R L P G G V A S P E D L W R L V A G G E D A I S E F P Q D R G W D V E G L Y D P N P E A T G K S Y A R E A G F L Y E A G E F D A D F F G I S P R E A L A M D P Q Q R L L L E A S W E A F E H A G I P A A T A R G T S V G V F T G V M Y H D Y A T R L T D V P E G I E G Y L G T G N S G S V A S G R V A Y T L G L E G P A V T V D T A C S S S L V A L H L A V Q A L R K G E V D M A L A G G V T V M S T P S T F V E F S R Q R G L A P D G R S K S F S S T A D G T S W S E G V G V L L V E R L S D A R R K G H R I L A V V R G T A V N Q D G A S S G L T A P N G P S Q Q R V I R R A L A D A R L T T S D V D V V E A H G T G T R L G D P I E A Q A V I A T Y G Q G R D G E Q P L R L G S L K S N I G H T Q A A A G V S G V I K M V Q A M R H G V L P K T L H V E K P T D Q V D W S A G A V E L L T E A M D W P D K G D G G L R R A A V S S F G V S G T N A H V V L E E A P A A E E T P A S E A T P A V E P S V G A G L V P W L V S A K T P A A L D A Q I G R L A A F A S Q G R T D A A D P G A V A R V L A G G R A E F E H R A V V L G T G Q D D F A Q A L T A P E G L I R G T P S D V G R V A F V F P G Q G T Q W A G M G A E L L D V S K E F A A A M A E C E S A L S R Y V D W S L E A V V R Q A P G A P T L E R V D V V Q P V T F A V M V S L A K V W Q H H G V T P Q A V V G H S Q G E I A A A Y V A G A L T L D D A A R V V T L R S K S I A A H L A G K G G M I S L A L S E E A T R Q R I E N L H G L S I A A V N G P T A T V V S G D P T Q I Q E L A Q A C E A D G V R A R I I P V D Y A S H S A H V E T I E S E L A E V L A G L S P R T P E V P F F S T L E G A W I T E P V L D G T Y W Y R N L R H R V G F A P A V E T L A T D E G F T H F I E V S A H P V L T M T L P E T V T G L G T L R R E Q G G Q E R L V T S L A E A W T N G L T I D W A P V L P T A T G H H P E L P T Y A F Q R R H Y W L H D S P A V Q G S V Q D S W R Y R I D W K R L A V A D A S E R A G L S G R W L V V V P E D R S A E A A P V L A A L S G A G A D P V Q L D V S P L G D R Q R L A A T L G E A L A A A G G A V D G V L S L L A W D E S A H P G H P A P F T R G T G A T L T L V Q A L E D A G V A A P L W C V T H G A V S V G R A D H V T S P A Q A M V W G M G R V A A L E H P E R W G G L I D L P S D A D R A A L D R M T T V L A G G T G E D Q V A V R A S G L L A R R L V R A S L P A H G T A S P W W Q A D G T V L V T G A E E P A A A E A A R R L A R D G A G H L L L H T T P S G S E G A E G T S G A A E D S G L A G L V A E L A D L G A T A T V V T C D L T D A E A A A R L L A G V S D A H P L S A V L H L P P T V D S E P L A A T D A D A L A R V V T A K A T A A L H L D R L L R E A A A A G G R P P V L V L F S S V A A I W G G A G Q G A Y A A G T A F L D A L A G Q H R A D G P T V T S V A W S P W E G S R V T E G A T G E R L R R L G L R P L A P A T A L T A L D T A L G H G D T A V T I A D V D W S S F A P G F T T A R P G T L L A D L P E A R R A L D E Q Q S T T A A D D T V L S R E L G A L T G A E Q Q R R M Q E L V R E H L A V V L N H P S P E A V D T G R A F R D L G F D S L T A V E L R N R L K N A T G L A L P A T L V F D Y P T P R T L A E F L L A E I L G E Q A G A G E Q L P V D G G V D D E P V A I V G M A C R L P G G V A S P E D L W R L V A G G E D A I S G F P Q D R G W D V E G L Y D P D P D A S G R T Y C R A G G F L D E A G E F D A D F F G I S P R E A L A M D P Q Q R L L L E T S W E A V E D A G I D P T S L Q G Q Q V G V F A G T N G P H Y E P L L R N T A E D L E G Y V G T G N A A S I M S G R V S Y T L G L E G P A V T V D T A C S S S L V A L H L A V Q A L R K G E C G L A L A G G V T V M S T P T T F V E F S R Q R G L A E D G R S K A F A A S A D G F G P A E G V G M L L V E R L S D A R R N G H R V L A V V R G S A V N Q D G A S N G L T A P N G P S Q Q R V I R R A L A D A R L T T A D V D V V E A H G T G T R L G D P I E A Q A L I A T Y G Q G R D T E Q P L R L G S L K S N I G H T Q A A A G V S G I I K M V Q A M R H G V L P K T L H V D R P S D Q I D W S A G T V E L L T E A M D W P R K Q E G G L R R A A V S S F G I S G T N A H I V L E E A P V D E D A P A D E P S V G G V V P W L V S A K T P A A L D A Q I G R L A A F A S Q G R T D A A D P G A V A R V L A G G R A Q F E H R A V A L G T G Q D D L A A A L A A P E G L V R G V A S G V G R V A F V F P G Q G T Q W A G M G A E L L D V S K E F A A A M A E C E A A L A P Y V D W S L E A V V R Q A P G A P T L E R V D V V Q P V T F A V M V S L A K V W Q H H G V T P Q A V V G H S Q G E I A A A Y V A G A L S L D D A A R V V T L R S K S I G A H L A G Q G G M L S L A L S E A A V V E R L A G F D G L S V A A V N G P T A T V V S G D P T Q I Q E L A Q A C E A D G V R A R I I P V D Y A S H S A H V E T I E S E L A D V L A G L S P Q T P Q V P F F S T L E G A W I T E P A L D G G Y W Y R N L R H R V G F A P A V E T L A T D E G F T H F V E V S A H P V L T M A L P E T V T G L G T L R R D N G G Q H R L T T S L A E A W A N G L T V D W A S L L P T T T T H P D L P T Y A F Q T E R Y W P Q P D L S A A G D I T S A G L G A A E H P L L G A A V A L A D S D G C L L T G S L S L R T H P W L A D H A V A G T V L L P G T A F V E L A F R A G D Q V G C D L V E E L T L D A P L V L P R R G A V R V Q L S V G A S D E S G R R T F G L Y A H P E D A P G E A E W T R H A T G V L A A R A D R T A P V A D P E A W P P P G A E P V D V D G L Y E R F A A N G Y G Y G P L F Q G V R G V W R R G D E V F A D V A L P A E V A G A E G A R F G L H P A L L D A A V Q A A G A G R G V R R G H A A A V R L E R D L L Y A V G A T A L R V R L A P A G P D T V S V S A A D S S G Q P V F A A D S L T V L P V D P A Q L A A F S D P T L D A L H L L E W T A W D G A A Q A L P G A V V L G G D A D G L A A A L R A G G T E V L S F P D L T D L V E A V D R G E T P A P A T V L V A C P A A G P D G P E H V R E A L H G S L A L M Q A W L A D E R F T D G R L V L V T R D A V A A R S G D G L R S T G Q A A V W G L G R S A Q T E S P G R F V L L D L A G E A R T A G D A T A G D G L T T G D A T V G G T S G D A A L G S A L A T A L G S G E P Q L A L R D G A L L V P R L A R A A A P A A A D G L A A A D G L A A L P L P A A P A L W R L E P G T D G S L E S L T A A P G D A E T L A P E P L G P G Q V R I A I R A T G L N F R D V L I A L G M Y P D P A L M G T E G A G V V T A T G P G V T H L A P G D R V M G L L S G A Y A P V V V A D A R T V A R M P E G W T F A Q G A S V P V V F L T A V Y A L R D L A D V K P G E R L L V H S A A G G V G M A A V Q L A R H W G V E V H G T A S H G K W D A L R A L G L D D A H I A S S R T L D F E S A F R A A S G G A G M D V V L N S L A R E F V D A S L R L L G P G G R F V E M G K T D V R D A E R V A A D H P G V G Y R A F D L G E A G P E R I G E M L A E V I A L F E D G V L R H L P V T T W D V R R A R D A F R H V S Q A R H T G K V V L T M P S G L D P E G T V L L T G G T G A L G G I V A R H V V G E W G V R R L L L V S R R G T D A P G A G E L V H E L E A L G A D V S V A A C D V A D R E A L T A V L D S I P A E H P L T A V V H T A G V L S D G T L P S M T A E D V E H V L R P K V D A A F L L D E L T S T P G Y D L A A F V M F S S A A A V F G G A G Q G A Y A A A N A T L D A L A W R R R T A G L P A L S L G W G L W A E T S G M T G G L S D T D R S R L A R S G A T P M D S E L T L S L L D A A M R R D D P A L V P I A L D V A A L R A Q Q R D G M L A P L L S G L T R G S R V G G A P V N Q R R A A A G G A G E A D T D L G G R L A A M T P D D R V A H L R D L V R T H V A T V L G H G T P S R V D L E R A F R D T G F D S L T A V E L R N R L N A A T G L R L P A T L V F D H P T P G E L A G H L L D E L A T A A G G S W A E G T G S G D T A S A T D R Q T T A A L A E L D R L E G V L A S L A P A A G G R P E L A A R L R A L A A A L G D D G D D A T D L D E A S D D D L F S F I D K E L G D S D F
Cofactor	COFACTOR: Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942; Evidence={ECO:0000305|PubMed:21570406}; Note=Binds 2 phosphopantetheines covalently. {ECO:0000305};
Active site	ACT_SITE 208 208 Acyl-thioester intermediate; for beta-ketoacyl synthase 1 activity. {ECO:0000255|PROSITE-ProRule:PRU10022}.; ACT_SITE 662 662 Acyl-ester intermediate; for acyltransferase 1 activity. {ECO:0000255|PROSITE-ProRule:PRU10022}.; ACT_SITE 1313 1313 For C2-type beta-ketoacyl reductase 1 and probable racemase activities. {ECO:0000250|UniProtKB:Q03132, ECO:0000305|PubMed:21570406}.; ACT_SITE 1712 1712 Acyl-thioester intermediate; for beta-ketoacyl synthase 2 activity. {ECO:0000255|PROSITE-ProRule:PRU10022}.; ACT_SITE 2159 2159 Acyl-ester intermediate; for acyltransferase 2 activity. {ECO:0000255|PROSITE-ProRule:PRU10022}.; ACT_SITE 2460 2460 Proton acceptor; for dehydratase activity. {ECO:0000250|UniProtKB:Q03132}.; ACT_SITE 2629 2629 Proton donor; for dehydratase activity. {ECO:0000250|UniProtKB:Q03132}.; ACT_SITE 3005 3005 For enoyl reductase activity. {ECO:0000250|UniProtKB:Q03132}.; ACT_SITE 3427 3427 For beta-ketoacyl reductase 2 activity. {ECO:0000305}.
Pfam	PF00698 PF08240 PF08990 PF16197 PF00109 PF02801 PF08659 PF00550 PF14765
InterPro	IPR001227 IPR036736 IPR014043 IPR016035 IPR013154 IPR011032 IPR032821 IPR018201 IPR014031 IPR014030 IPR016036 IPR036291 IPR020801 IPR020841 IPR020807 IPR042104 IPR020843 IPR013968 IPR020806 IPR015083 IPR009081 IPR006162 IPR002364 IPR016039