Uniprot ID	Q9ZGI5
Uniprot Name	PIKA1_STRVZ
Taxonomy ID	54571
Sequence	M S S A G I T R T G A R T P V T G R G A A A W D T G E V R V R R G L P P A G P D H A E H S F S R A P T G D V R A E L I R G E M S T V S K S E S E E F V S V S N D A G S A H G T A E P V A V V G I S C R V P G A R D P R E F W E L L A A G G Q A V T D V P A D R W N A G D F Y D P D R S A P G R S N S R W G G F I E D V D R F D A A F F G I S P R E A A E M D P Q Q R L A L E L G W E A L E R A G I D P S S L T G T R T G V F A G A I W D D Y A T L K H R Q G G A A I T P H T V T G L H R G I I A N R L S Y T L G L R G P S M V V D S G Q S S S L V A V H L A C E S L R R G E S E L A L A G G V S L N L V P D S I I G A S K F G G L S P D G R A Y T F D A R A N G Y V R G E G G G F V V L K R L S R A V A D G D P V L A V I R G S A V N N G G A A Q G M T T P D A Q A Q E A V L R E A H E R A G T A P A D V R Y V E L H G T G T P V G D P I E A A A L G A A L G T G R P A G Q P L L V G S V K T N I G H L E G A A G I A G L I K A V L A V R G R A L P A S L N Y E T P N P A I P F E E L N L R V N T E Y L P W E P E H D G Q R M V V G V S S F G M G G T N A H V V L E E A P G G C R G A S V V E S T V G G S A V G G G V V P W V V S A K S A A A L D A Q I E R L A A F A S R D R T D G V D A G A V D A G A V D A G A V A R V L A G G R A Q F E H R A V V V G S G P D D L A A A L A A P E G L V R G V A S G V G R V A F V F P G Q G T Q W A G M G A E L L D S S A V F A A A M A E C E A A L S P Y V D W S L E A V V R Q A P G A P T L E R V D V V Q P V T F A V M V S L A R V W Q H H G V T P Q A V V G H S Q G E I A A A Y V A G A L S L D D A A R V V T L R S K S I A A H L A G K G G M L S L A L S E D A V L E R L A G F D G L S V A A V N G P T A T V V S G D P V Q I E E L A R A C E A D G V R A R V I P V D Y A S H S R Q V E I I E S E L A E V L A G L S P Q A P R V P F F S T L E G A W I T E P V L D G G Y W Y R N L R H R V G F A P A V E T L A T D E G F T H F V E V S A H P V L T M A L P G T V T G L A T L R R D N G G Q D R L V A S L A E A W A N G L A V D W S P L L P S A T G H H S D L P T Y A F Q T E R H W L G E I E A L A P A G E P A V Q P A V L R T E A A E P A E L D R D E Q L R V I L D K V R A Q T A Q V L G Y A T G G Q I E V D R T F R E A G C T S L T G V D L R N R I N A A F G V R M A P S M I F D F P T P E A L A E Q L L L V V H G E A A A N P A G A E P A P V A A A G A V D E P V A I V G M A C R L P G G V A S P E D L W R L V A G G G D A I S E F P Q D R G W D V E G L Y H P D P E H P G T S Y V R Q G G F I E N V A G F D A A F F G I S P R E A L A M D P Q Q R L L L E T S W E A V E D A G I D P T S L R G R Q V G V F T G A M T H E Y G P S L R D G G E G L D G Y L L T G N T A S V M S G R V S Y T L G L E G P A L T V D T A C S S S L V A L H L A V Q A L R K G E V D M A L A G G V A V M P T P G M F V E F S R Q R G L A G D G R S K A F A A S A D G T S W S E G V G V L L V E R L S D A R R N G H Q V L A V V R G S A L N Q D G A S N G L T A P N G P S Q Q R V I R R A L A D A R L T T S D V D V V E A H G T G T R L G D P I E A Q A L I A T Y G Q G R D D E Q P L R L G S L K S N I G H T Q A A A G V S G V I K M V Q A M R H G L L P K T L H V D E P S D Q I D W S A G A V E L L T E A V D W P E K Q D G G L R R A A V S S F G I S G T N A H V V L E E A P V V V E G A S V V E P S V G G S A V G G G V T P W V V S A K S A A A L D A Q I E R L A A F A S R D R T D D A D A G A V D A G A V A H V L A D G R A Q F E H R A V A L G A G A D D L V Q A L A D P D G L I R G T A S G V G R V A F V F P G Q G T Q W A G M G A E L L D S S A V F A A A M A E C E A A L S P Y V D W S L E A V V R Q A P G A P T L E R V D V V Q P V T F A V M V S L A R V W Q H H G V T P Q A V V G H S Q G E I A A A Y V A G A L P L D D A A R V V T L R S K S I A A H L A G K G G M L S L A L N E D A V L E R L S D F D G L S V A A V N G P T A T V V S G D P V Q I E E L A Q A C K A D G F R A R I I P V D Y A S H S R Q V E I I E S E L A Q V L A G L S P Q A P R V P F F S T L E G T W I T E P V L D G T Y W Y R N L R H R V G F A P A I E T L A V D E G F T H F V E V S A H P V L T M T L P E T V T G L G T L R R E Q G G Q E R L V T S L A E A W V N G L P V A W T S L L P A T A S R P G L P T Y A F Q A E R Y W L E N T P A A L A T G D D W R Y R I D W K R L P A A E G S E R T G L S G R W L A V T P E D H S A Q A A A V L T A L V D A G A K V E V L T A G A D D D R E A L A A R L T A L T T G D G F T G V V S L L D G L V P Q V A W V Q A L G D A G I K A P L W S V T Q G A V S V G R L D T P A D P D R A M L W G L G R V V A L E H P E R W A G L V D L P A Q P D A A A L A H L V T A L S G A T G E D Q I A I R T T G L H A R R L A R A P L H G R R P T R D W Q P H G T V L I T G G T G A L G S H A A R W M A H H G A E H L L L V S R S G E Q A P G A T Q L T A E L T A S G A R V T I A A C D V A D P H A M R T L L D A I P A E T P L T A V V H T A G A L D D G I V D T L T A E Q V R R A H R A K A V G A S V L D E L T R D L D L D A F V L F S S V S S T L G I P G Q G N Y A P H N A Y L D A L A A R R R A T G R S A V S V A W G P W D G G G M A A G D G V A E R L R N H G V P G M D P E L A L A A L E S A L G R D E T A I T V A D I D W D R F Y L A Y S S G R P Q P L V E E L P E V R R I I D A R D S A T S G Q G G S S A Q G A N P L A E R L A A A A P G E R T E I L L G L V R A Q A A A V L R M R S P E D V A A D R A F K D I G F D S L A G V E L R N R L T R A T G L Q L P A T L V F D H P T P L A L V S L L R S E F L G D E E T A D A R R S A A L P A T V G A G A G A G A G T D A D D D P I A I V A M S C R Y P G D I R S P E D L W R M L S E G G E G I T P F P T D R G W D L D G L Y D A D P D A L G R A Y V R E G G F L H D A A E F D A E F F G V S P R E A L A M D P Q Q R M L L T T S W E A F E R A G I E P A S L R G S S T G V F I G L S Y Q D Y A A R V P N A P R G V E G Y L L T G S T P S V A S G R I A Y T F G L E G P A T T V D T A C S S S L T A L H L A V R A L R S G E C T M A L A G G V A M M A T P H M F V E F S R Q R A L A P D G R S K A F S A D A D G F G A A E G V G L L L V E R L S D A R R N G H P V L A V V R G T A V N Q D G A S N G L T A P N G P S Q Q R V I R Q A L A D A R L A P G D I D A V E T H G T G T S L G D P I E A Q G L Q A T Y G K E R P A E R P L A I G S V K S N I G H T Q A A A G A A G I I K M V L A M R H G T L P K T L H A D E P S P H V D W A N S G L A L V T E P I D W P A G T G P R R A A V S S F G I S G T N A H V V L E Q A P D A A G E V L G A D E V P E V S E T V A M A G T A G T S E V A E G S E A S E A P A A P G S R E A S L P G H L P W V L S A K D E Q S L R G Q A A A L H A W L S E P A A D L S D A D G P A R L R D V G Y T L A T S R T A F A H R A A V T A A D R D G F L D G L A T L A Q G G T S A H V H L D T A R D G T T A F L F T G Q G S Q R P G A G R E L Y D R H P V F A R A L D E I C A H L D G H L E L P L L D V M F A A E G S A E A A L L D E T R Y T Q C A L F A L E V A L F R L V E S W G M R P A A L L G H S V G E I A A A H V A G V F S L A D A A R L V A A R G R L M Q E L P A G G A M L A V Q A A E D E I R V W L E T E E R Y A G R L D V A A V N G P E A A V L S G D A D A A R E A E A Y W S G L G R R T R A L R V S H A F H S A H M D G M L D G F R A V L E T V E F R R P S L T V V S N V T G L A A G P D D L C D P E Y W V R H V R G T V R F L D G V R V L R D L G V R T C L E L G P D G V L T A M A A D G L A D T P A D S A A G S P V G S P A G S P A D S A A G A L R P R P L L V A L L R R K R S E T E T V A D A L G R A H A H G T G P D W H A W F A G S G A H R V D L P T Y S F R R D R Y W L D A P A A D T A V D T A G L G L G T A D H P L L G A V V S L P D R D G L L L T G R L S L R T H P W L A D H A V L G S V L L P G A A M V E L A A H A A E S A G L R D V R E L T L L E P L V L P E H G G V E L R V T V G A P A G E P G G E S A G D G A R P V S L H S R L A D A P A G T A W S C H A T G L L A T D R P E L P V A P D R A A M W P P Q G A E E V P L D G L Y E R L D G N G L A F G P L F Q G L N A V W R Y E G E V F A D I A L P A T T N A T A P A T A N G G G S A A A A P Y G I H P A L L D A S L H A I A V G G L V D E P E L V R V P F H W S G V T V H A A G A A A A R V R L A S A G T D A V S L S L T D G E G R P L V S V E R L T L R P V T A D Q A A A S R V G G L M H R V A W R P Y A L A S S G E Q D P H A T S Y G P T A V L G K D E L K V A A A L E S A G V E V G L Y P D L A A L S Q D V A A G A P A P R T V L A P L P A G P A D G G A E G V R G T V A R T L E L L Q A W L A D E H L A G T R L L L V T R G A V R D P E G S G A D D G G E D L S H A A A W G L V R T A Q T E N P G R F G L L D L A D D A S S Y R T L P S V L S D A G L R D E P Q L A L H D G T I R L A R L A S V R P E T G T A A P A L A P E G T V L L T G G T G G L G G L V A R H V V G E W G V R R L L L V S R R G T D A P G A D E L V H E L E A L G A D V S V A A C D V A D R E A L T A V L D A I P A E H P L T A V V H T A G V L S D G T L P S M T T E D V E H V L R P K V D A A F L L D E L T S T P A Y D L A A F V M F S S A A A V F G G A G Q G A Y A A A N A T L D A L A W R R R A A G L P A L S L G W G L W A E T S G M T G E L G Q A D L R R M S R A G I G G I S D A E G I A L L D A A L R D D R H P V L L P L R L D A A G L R D A A G N D P A G I P A L F R D V V G A R T V R A R P S A A S A S T T A G T A G T P G T A D G A A E T A A V T L A D R A A T V D G P A R Q R L L L E F V V G E V A E V L G H A R G H R I D A E R G F L D L G F D S L T A V E L R N R L N S A G G L A L P A T L V F D H P S P A A L A S H L D A E L P R G A S D Q D G A G N R N G N E N G T T A S R S T A E T D A L L A Q L T R L E G A L V L T G L S D A P G S E E V L E H L R S L R S M V T G E T G T G T A S G A P D G A G S G A E D R P W A A G D G A G G G S E D G A G V P D F M N A S A E E L F G L L D Q D P S T D
Cofactor	COFACTOR: Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942; Evidence={ECO:0000305|PubMed:19027305}; Note=Binds 3 phosphopantetheines covalently. {ECO:0000305};
Active site	ACT_SITE 724 724 Acyl-ester intermediate; for acyltransferase 1 activity. {ECO:0000305}.; ACT_SITE 1281 1281 Acyl-thioester intermediate; for beta-ketoacyl synthase 2 activity. {ECO:0000255|PROSITE-ProRule:PRU10022, ECO:0000305|PubMed:19437523}.; ACT_SITE 1740 1740 Acyl-ester intermediate; for acyltransferase 2 activity. {ECO:0000250|UniProtKB:Q03133, ECO:0000255|PROSITE-ProRule:PRU10022}.; ACT_SITE 2355 2355 For beta-ketoacyl reductase 1 activity. {ECO:0000250|UniProtKB:Q03131, ECO:0000250|UniProtKB:Q03132}.; ACT_SITE 2776 2776 Acyl-thioester intermediate; for beta-ketoacyl synthase 3 activity. {ECO:0000255|PROSITE-ProRule:PRU10022}.; ACT_SITE 3273 3273 Acyl-ester intermediate; for acyltransferase 3 activity. {ECO:0000250|UniProtKB:Q03133, ECO:0000255|PROSITE-ProRule:PRU10022}.; ACT_SITE 4250 4250 For beta-ketoacyl reductase 2 activity. {ECO:0000250|UniProtKB:Q03131, ECO:0000250|UniProtKB:Q03132}.
Pfam	PF00698 PF16197 PF00109 PF02801 PF08659 PF00550 PF14765
InterPro	IPR001227 IPR036736 IPR014043 IPR016035 IPR032821 IPR018201 IPR014031 IPR014030 IPR016036 IPR036291 IPR020801 IPR020841 IPR020807 IPR042104 IPR013968 IPR020806 IPR009081 IPR006162 IPR016039