TitleDatePubMed ID
Metal Ions Play an Essential Catalytic Role in the Mechanism of Ketol-Acid Reductoisomerase.2016 May 2327136273
Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 Å resolution - a potential target for anti-tuberculosis drug discovery.2016 Apr26876563
Cofactor specificity motifs and the induced fit mechanism in class I ketol-acid reductoisomerases.2015 Jun 1525849365
Molecular annotation of ketol-acid reductoisomerases from Streptomyces reveals a novel amino acid biosynthesis interlock mediated by enzyme promiscuity.2015 Mar25296650
Identification and optimization of a novel thermo- and solvent stable ketol-acid reductoisomerase for cell free isobutanol biosynthesis.2015 Jan25446654
Production of 2-butanol from crude glycerol by a genetically-engineered Klebsiella pneumoniae strain.2014 Jan24078128
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH.2013 Jul 223776225
Bacterial and plant ketol-acid reductoisomerases have different mechanisms of induced fit during the catalytic cycle.2012 Dec 723036858
High throughput receptor-based virtual screening under ZINC database, synthesis, and biological evaluation of ketol-acid reductoisomerase inhibitors.2010 Feb20028400
Conformational changes in a plant ketol-acid reductoisomerase upon Mg(2+) and NADPH binding as revealed by two crystal structures.2009 May 2919362563