Title | Date | PubMed ID |
Metal Ions Play an Essential Catalytic Role in the Mechanism of Ketol-Acid Reductoisomerase. | 2016 May 23 | 27136273 |
Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 Å resolution - a potential target for anti-tuberculosis drug discovery. | 2016 Apr | 26876563 |
Cofactor specificity motifs and the induced fit mechanism in class I ketol-acid reductoisomerases. | 2015 Jun 15 | 25849365 |
Molecular annotation of ketol-acid reductoisomerases from Streptomyces reveals a novel amino acid biosynthesis interlock mediated by enzyme promiscuity. | 2015 Mar | 25296650 |
Identification and optimization of a novel thermo- and solvent stable ketol-acid reductoisomerase for cell free isobutanol biosynthesis. | 2015 Jan | 25446654 |
Production of 2-butanol from crude glycerol by a genetically-engineered Klebsiella pneumoniae strain. | 2014 Jan | 24078128 |
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH. | 2013 Jul 2 | 23776225 |
Bacterial and plant ketol-acid reductoisomerases have different mechanisms of induced fit during the catalytic cycle. | 2012 Dec 7 | 23036858 |
High throughput receptor-based virtual screening under ZINC database, synthesis, and biological evaluation of ketol-acid reductoisomerase inhibitors. | 2010 Feb | 20028400 |
Conformational changes in a plant ketol-acid reductoisomerase upon Mg(2+) and NADPH binding as revealed by two crystal structures. | 2009 May 29 | 19362563 |