TitleDatePubMed ID
Mechanism for cyclization reaction by clavaminic acid synthase. Insights from modeling studies.2007 Mar 2717323933
New reactions in clavulanic acid biosynthesis.2002 Oct12413541
Crystal structure of a clavaminate synthase-Fe(II)-2-oxoglutarate-substrate-NO complex: evidence for metal centered rearrangements.2002 Apr 2412062399
Spectroscopic studies of substrate interactions with clavaminate synthase 2, a multifunctional alpha-KG-dependent non-heme iron enzyme: correlation with mechanisms and reactivities.2001 Aug 111472170
Mutagenesis studies on the iron binding ligands of clavaminic acid synthase.2000 Dec 911112446
Site-directed mutagenesis and biochemical analysis of the endogenous ligands in the ferrous active site of clavaminate synthase. The His-3 variant of the 2-His-1-carboxylate model.2000 Jul 2510913275
Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.2000 Feb10655615
A single monomeric iron center in clavaminate synthase catalyzes three nonsuccessive oxidative transformations.1996 Jul8831977
Purification and characterization of clavaminate synthase from Streptomyces antibioticus. A multifunctional enzyme of clavam biosynthesis.1995 Mar 107890654
Expression and purification of two isozymes of clavaminate synthase and initial characterization of the iron binding site. General error analysis in polymerase chain reaction amplification.1995 Mar 37876185