Title | Date | PubMed ID |
Nitric oxide stimulates cellular degradation of human CYP51A1, the highly conserved lanosterol 14α-demethylase. | 2017 Sep 14 | 28830911 |
An overview of azoles targeting sterol 14α-demethylase for antileishmanial therapy. | 2017 Jul 28 | 28456033 |
Structural analyses of <i>Candida albicans</i> sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis. | 2017 Apr 21 | 28258218 |
Design, Synthesis and Antifungal Activity Evaluation of New Thiazolin-4-ones as Potential Lanosterol 14α-Demethylase Inhibitors. | 2017 Jan 17 | 28106743 |
Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals. | 2016 | 27907120 |
The amino acid substitution N136Y in Candida albicans sterol 14alpha-demethylase is involved in fluconazole resistance. | 2016 Oct 1 | 27143634 |
Azole Antifungal Sensitivity of Sterol 14α-Demethylase (CYP51) and CYP5218 from Malassezia globosa. | 2016 Jun 13 | 27291783 |
Structural basis for rational design of inhibitors targeting Trypanosoma cruzi sterol 14α-demethylase: two regions of the enzyme molecule potentiate its inhibition. | 2014 Aug 14 | 25033013 |
Identification, modeling and ligand affinity of early deuterostome CYP51s, and functional characterization of recombinant zebrafish sterol 14α-demethylase. | 2014 Jun | 24361620 |
Imidazolylchromanones containing alkyl side chain as lanosterol 14α-demethylase inhibitors: synthesis, antifungal activity and docking study. | 2014 Apr | 23488742 |