Title | Date | PubMed ID |
The impact of the clinical CYP11B2 mutation V386A strongly depends on the enzyme's genetic background. | 2017 Apr 29 | 28190867 |
Different effects of progesterone and estradiol on chimeric and wild type aldosterone synthase in vitro. | 2013 Aug 13 | 23938178 |
Structural insights into aldosterone synthase substrate specificity and targeted inhibition. | 2013 Feb | 23322723 |
Human aldosterone synthase: recombinant expression in E. coli and purification enables a detailed biochemical analysis of the protein on the molecular level. | 2012 Oct | 22446688 |
Very-low-density lipoprotein mediates transcriptional regulation of aldosterone synthase in human adrenocortical cells through multiple signaling pathways. | 2012 Apr | 22331364 |
Alteration in accumulated aldosterone synthesis as a result of N-terminal cleavage of aldosterone synthase. | 2012 Mar | 22184340 |
Fine-tuning the selectivity of aldosterone synthase inhibitors: structure-activity and structure-selectivity insights from studies of heteroaryl substituted 1,2,5,6-tetrahydropyrrolo[3,2,1-ij]quinolin-4-one derivatives. | 2011 Apr 14 | 21384875 |
N-(Pyridin-3-yl)benzamides as selective inhibitors of human aldosterone synthase (CYP11B2). | 2011 Jan 1 | 21129965 |
The discovery of potent inhibitors of aldosterone synthase that exhibit selectivity over 11-beta-hydroxylase. | 2010 Aug 1 | 20615692 |
Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). | 2010 Feb 25 | 20121113 |