Title | Date | PubMed ID |
Probing Ligand Exchange in the P450 Enzyme CYP121 from Mycobacterium tuberculosis: Dynamic Equilibrium of the Distal Heme Ligand as a Function of pH and Temperature. | 2017 Dec 6 | 29090577 |
Biophysical Screening of a Focused Library for the Discovery of CYP121 Inhibitors as Novel Antimycobacterials. | 2017 Oct 9 | 28815923 |
Cross-linking of dicyclotyrosine by the cytochrome P450 enzyme CYP121 from <i>Mycobacterium tuberculosis</i> proceeds through a catalytic shunt pathway. | 2017 Aug 18 | 28667013 |
Substrate Fragmentation for the Design of M. tuberculosis CYP121 Inhibitors. | 2016 Sep 6 | 27432475 |
QM/MM study of the C-C coupling reaction mechanism of CYP121, an essential cytochrome p450 of Mycobacterium tuberculosis. | 2014 Jun | 24356896 |
Nanoelectrospray ionization mass spectrometric study of Mycobacterium tuberculosis CYP121-ligand interactions. | 2013 Jun 18 | 23675886 |
Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121: insights from biochemical studies and crystal structures. | 2013 Jun 14 | 23620594 |
Application of fragment screening and merging to the discovery of inhibitors of the Mycobacterium tuberculosis cytochrome P450 CYP121. | 2012 Sep 10 | 22890978 |
Molecular docking of azole drugs and their analogs on CYP121 of Mycobacterium tuberculosis. | 2011 | 22125383 |
Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis. | 2009 May 5 | 19416919 |