Title | Date | PubMed ID |
Engineering deacetoxycephalosporin C synthase as a catalyst for the bioconversion of penicillins. | 2017 May | 27826726 |
Reconstitution of TCA cycle with DAOCS to engineer Escherichia coli into an efficient whole cell catalyst of penicillin G. | 2015 Aug 11 | 26216972 |
Studies on deacetoxycephalosporin C synthase support a consensus mechanism for 2-oxoglutarate dependent oxygenases. | 2014 Apr 22 | 24684493 |
Iterative combinatorial mutagenesis as an effective strategy for generation of deacetoxycephalosporin C synthase with improved activity toward penicillin G. | 2012 Nov | 22923414 |
New strategy of site-directed mutagenesis identifies new sites to improve Streptomyces clavuligerus deacetoxycephalosporin C synthase activity toward penicillin G. | 2012 Mar | 21909691 |
Expression of cefF significantly decreased deacetoxycephalosporin C formation during cephalosporin C production in Acremonium chrysogenum. | 2012 Feb | 21866341 |
Saturation mutagenesis of Acremonium chrysogenum deacetoxy/deacetylcephalosporin C synthase R308 site confirms its role in controlling substrate specificity. | 2011 Apr | 21190060 |
Directed evolution and rational approaches to improving Streptomyces clavuligerus deacetoxycephalosporin C synthase for cephalosporin production. | 2009 May | 19277744 |
Chapter 16. Enzymology of beta-lactam compounds with cephem structure produced by actinomycete. | 2009 | 19374992 |
A complete library of amino acid alterations at R306 in Streptomyces clavuligerus deacetoxycephalosporin C synthase demonstrates its structural role in the ring-expansion activity. | 2008 Feb 15 | 17729280 |