Title | Date | PubMed ID |
Taxadiene-5α-ol is a minor product of CYP725A4 when expressed in Escherichia coli. | 2018 May | 28876471 |
Heterologous expression and characterization of plant Taxadiene-5α-Hydroxylase (CYP725A4) in Escherichia coli. | 2017 Apr | 28109855 |
Engineering of Taxadiene Synthase for Improved Selectivity and Yield of a Key Taxol Biosynthetic Intermediate. | 2017 Feb 17 | 27794603 |
Orthogonal Assays Clarify the Oxidative Biochemistry of Taxol P450 CYP725A4. | 2016 May 20 | 26930136 |
Mechanistic Insights into Taxadiene Epoxidation by Taxadiene-5α-Hydroxylase. | 2016 Feb 19 | 26677870 |
CYP725A4 from yew catalyzes complex structural rearrangement of taxa-4(5),11(12)-diene into the cyclic ether 5(12)-oxa-3(11)-cyclotaxane. | 2008 Mar 7 | 18167342 |
Cytochrome p450 taxadiene 5alpha-hydroxylase, a mechanistically unusual monooxygenase catalyzing the first oxygenation step of taxol biosynthesis. | 2004 Mar | 15123267 |
Taxol biosynthetic genes. | 2001 Sep | 11524108 |
Taxol biosynthesis: differential transformations of taxadien-5 alpha-ol and its acetate ester by cytochrome P450 hydroxylases from Taxus suspension cells. | 2001 Jun 15 | 11396929 |
Cytochrome P450-catalyzed hydroxylation of taxa-4(5),11(12)-diene to taxa-4(20),11(12)-dien-5alpha-ol: the first oxygenation step in taxol biosynthesis. | 1996 Jun | 8807878 |