Title | Date | PubMed ID |
Pharmacophore mapping, molecular docking, chemical synthesis of some novel pyrrolyl benzamide derivatives and evaluation of their inhibitory activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis. | 2018 Dec | 30223149 |
Discovery of a cofactor-independent inhibitor of <i>Mycobacterium tuberculosis</i> InhA. | 2018 Jun | 30456352 |
An overview on crystal structures of InhA protein: Apo-form, in complex with its natural ligands and inhibitors. | 2018 Feb 25 | 29407960 |
Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors. | 2017 Mar 8 | 28151657 |
N-Benzyl-4-((heteroaryl)methyl)benzamides: A New Class of Direct NADH-Dependent 2-trans Enoyl-Acyl Carrier Protein Reductase (InhA) Inhibitors with Antitubercular Activity. | 2016 Apr 5 | 26934341 |
Piperazine derivatives: synthesis, inhibition of the Mycobacterium tuberculosis enoyl-acyl carrier protein reductase and SAR studies. | 2015 Jan 27 | 25461892 |
Development of 2-(4-oxoquinazolin-3(4H)-yl)acetamide derivatives as novel enoyl-acyl carrier protein reductase (InhA) inhibitors for the treatment of tuberculosis. | 2014 Oct 30 | 25218910 |
Conformational changes in 2-trans-enoyl-ACP (CoA) reductase (InhA) from M. tuberculosis induced by an inorganic complex: a molecular dynamics simulation study. | 2012 May | 21833828 |
Targeting InhA, the FASII enoyl-ACP reductase: SAR studies on novel inhibitor scaffolds. | 2012 | 22283812 |
Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis. | 2010 Dec | 21143326 |