TitleDatePubMed ID
Structure and kinetics assays of recombinant Schistosoma mansoni dihydrofolate reductase.2017 Jun28288799
Expression, purification and enzymatic characterization of Brugia malayi dihydrofolate reductase.2016 Dec27544923
Trypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate Synthase.2016 May27175479
Substrate channeling between the human dihydrofolate reductase and thymidylate synthase.2016 Jan26096018
Ligand binding studies, preliminary structure-activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase.2015 Oct 2026414808
An active second dihydrofolate reductase enzyme is not a feature of rat and mouse, but they do have activity in their mitochondria.2015 Jul 825980602
Structure-activity correlations for three pyrido[2,3-d]pyrimidine antifolates binding to human and Pneumocystis carinii dihydrofolate reductase.2015 Jun26057816
Insights into the slow-onset tight-binding inhibition of Escherichia coli dihydrofolate reductase: detailed mechanistic characterization of pyrrolo [3,2-f] quinazoline-1,3-diamine and its derivatives as novel tight-binding inhibitors.2015 May25703118
Effects of salt on the structure, stability, and function of a halophilic dihydrofolate reductase from a hyperhalophilic archaeon, Haloarcula japonica strain TR-1.2015 Mar25617115
Escherichia coli dihydrofolate reductase catalyzed proton and hydride transfers: temporal order and the roles of Asp27 and Tyr100.2014 Dec 2325453098