Title | Date | PubMed ID |
Structure and kinetics assays of recombinant Schistosoma mansoni dihydrofolate reductase. | 2017 Jun | 28288799 |
Expression, purification and enzymatic characterization of Brugia malayi dihydrofolate reductase. | 2016 Dec | 27544923 |
Trypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate Synthase. | 2016 May | 27175479 |
Substrate channeling between the human dihydrofolate reductase and thymidylate synthase. | 2016 Jan | 26096018 |
Ligand binding studies, preliminary structure-activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase. | 2015 Oct 20 | 26414808 |
An active second dihydrofolate reductase enzyme is not a feature of rat and mouse, but they do have activity in their mitochondria. | 2015 Jul 8 | 25980602 |
Structure-activity correlations for three pyrido[2,3-d]pyrimidine antifolates binding to human and Pneumocystis carinii dihydrofolate reductase. | 2015 Jun | 26057816 |
Insights into the slow-onset tight-binding inhibition of Escherichia coli dihydrofolate reductase: detailed mechanistic characterization of pyrrolo [3,2-f] quinazoline-1,3-diamine and its derivatives as novel tight-binding inhibitors. | 2015 May | 25703118 |
Effects of salt on the structure, stability, and function of a halophilic dihydrofolate reductase from a hyperhalophilic archaeon, Haloarcula japonica strain TR-1. | 2015 Mar | 25617115 |
Escherichia coli dihydrofolate reductase catalyzed proton and hydride transfers: temporal order and the roles of Asp27 and Tyr100. | 2014 Dec 23 | 25453098 |