TitleDatePubMed ID
An integrated approach towards the discovery of novel non-nucleoside Leishmania major pteridine reductase 1 inhibitors.2017 May 2628407565
Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity.2017 Mar 828282886
Molecular characterization and functional analysis of pteridine reductase in wild-type and antimony-resistant Leishmania lines.2016 Jan26689884
Structure-based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1.2014 Aug 1425007262
Leishmania donovani pteridine reductase 1: comparative protein modeling and protein-ligand interaction studies of the leishmanicidal constituents isolated from the fruits of Piper longum.2012 Dec22752544
Dissecting the metabolic roles of pteridine reductase 1 in Trypanosoma brucei and Leishmania major.2011 Mar 2521239486
Design, synthesis and biological evaluation of novel inhibitors of Trypanosoma brucei pteridine reductase 1.2011 Feb 721275054
Structure of recombinant Leishmania donovani pteridine reductase reveals a disordered active site.2011 Jan 121206018
Trypanosoma brucei pteridine reductase 1 is essential for survival in vitro and for virulence in mice.2010 Aug20545846
Molecular docking, structure-activity relationship and biological evaluation of the anticancer drug monastrol as a pteridine reductase inhibitor in a clinical isolate of Leishmania donovani.2010 Aug20519355