TitleDatePubMed ID
Trypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate Synthase.2016 May27175479
Substrate channeling between the human dihydrofolate reductase and thymidylate synthase.2016 Jan26096018
The influence of active site conformations on the hydride transfer step of the thymidylate synthase reaction mechanism.2015 Dec 1425868526
Activation of Two Sequential H-transfers in the Thymidylate Synthase Catalyzed Reaction.2015 Oct 226576323
Internalization and stability of a thymidylate synthase Peptide inhibitor in ovarian cancer cells.2014 Dec 2625353379
Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase.2014 Sep 125127103
Crystal structure of mouse thymidylate synthase in tertiary complex with dUMP and raltitrexed reveals N-terminus architecture and two different active site conformations.201424995339
First three-dimensional structure of Toxoplasma gondii thymidylate synthase-dihydrofolate reductase: insights for catalysis, interdomain interactions, and substrate channeling.2013 Oct 1524053355
Biochemical characterization of the bifunctional enzyme dihydrofolate reductase-thymidylate synthase from Leishmania (Viannia) and its evaluation as a drug target.2013 Jul-Sep24652175
Crystal structure of a flavin-dependent thymidylate synthase from Helicobacter pylori strain 26695.2012 Nov22512654