Title | Date | PubMed ID |
Trypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate Synthase. | 2016 May | 27175479 |
Substrate channeling between the human dihydrofolate reductase and thymidylate synthase. | 2016 Jan | 26096018 |
The influence of active site conformations on the hydride transfer step of the thymidylate synthase reaction mechanism. | 2015 Dec 14 | 25868526 |
Activation of Two Sequential H-transfers in the Thymidylate Synthase Catalyzed Reaction. | 2015 Oct 2 | 26576323 |
Internalization and stability of a thymidylate synthase Peptide inhibitor in ovarian cancer cells. | 2014 Dec 26 | 25353379 |
Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase. | 2014 Sep 1 | 25127103 |
Crystal structure of mouse thymidylate synthase in tertiary complex with dUMP and raltitrexed reveals N-terminus architecture and two different active site conformations. | 2014 | 24995339 |
First three-dimensional structure of Toxoplasma gondii thymidylate synthase-dihydrofolate reductase: insights for catalysis, interdomain interactions, and substrate channeling. | 2013 Oct 15 | 24053355 |
Biochemical characterization of the bifunctional enzyme dihydrofolate reductase-thymidylate synthase from Leishmania (Viannia) and its evaluation as a drug target. | 2013 Jul-Sep | 24652175 |
Crystal structure of a flavin-dependent thymidylate synthase from Helicobacter pylori strain 26695. | 2012 Nov | 22512654 |