Title | Date | PubMed ID |
Catechol-based substrates of chalcone synthase as a scaffold for novel inhibitors of PqsD. | 2015 Jan 27 | 25437621 |
From in vitro to in cellulo: structure-activity relationship of (2-nitrophenyl)methanol derivatives as inhibitors of PqsD in Pseudomonas aeruginosa. | 2014 Aug 28 | 24909330 |
Mechanistic details for anthraniloyl transfer in PqsD: the initial step in HHQ biosynthesis. | 2014 Jun | 24842325 |
Benzamidobenzoic acids as potent PqsD inhibitors for the treatment of Pseudomonas aeruginosa infections. | 2014 Apr 9 | 24589489 |
Biochemical and biophysical analysis of a chiral PqsD inhibitor revealing tight-binding behavior and enantiomers with contrary thermodynamic signatures. | 2013 Dec 20 | 24099650 |
The end of an old hypothesis: the pseudomonas signaling molecules 4-hydroxy-2-alkylquinolines derive from fatty acids, not 3-ketofatty acids. | 2013 Dec 19 | 24239007 |
Structure optimization of 2-benzamidobenzoic acids as PqsD inhibitors for Pseudomonas aeruginosa infections and elucidation of binding mode by SPR, STD NMR, and molecular docking. | 2013 Aug 8 | 23834469 |
Molecular basis of HHQ biosynthesis: molecular dynamics simulations, enzyme kinetic and surface plasmon resonance studies. | 2013 Aug 1 | 23916145 |
Validation of PqsD as an anti-biofilm target in Pseudomonas aeruginosa by development of small-molecule inhibitors. | 2012 Oct 3 | 22992202 |
Biosynthesis of 2-Alkyl-4(1H)-quinolones in Pseudomonas aeruginosa: potential for therapeutic interference with pathogenicity. | 2011 Apr 11 | 21425231 |