Title | Date | PubMed ID |
Structure-based binding between protein farnesyl transferase and PRL-PTP of malaria parasite: an interaction study of prenylation process in Plasmodium. | 2016 Dec | 26727035 |
Analogs of farnesyl diphosphate alter CaaX substrate specificity and reactions rates of protein farnesyltransferase. | 2016 Feb 15 | 26803203 |
Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors. | 2016 Feb 15 | 26774924 |
Mammalian farnesyltransferase α subunit regulates vacuolar protein sorting-associated protein 4A (Vps4A)--dependent intracellular trafficking through recycling endosomes. | 2015 Dec 25 | 26551458 |
Farnesyltransferase and geranylgeranyltransferase I: structures, mechanism, inhibitors and molecular modeling. | 2015 Feb | 25450772 |
Rapid analysis of protein farnesyltransferase substrate specificity using peptide libraries and isoprenoid diphosphate analogues. | 2014 Aug 15 | 24841702 |
Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design. | 2014 Mar | 24347326 |
Synthesis and biological evaluation of a new series of N-ylides as protein farnesyltransferase inhibitors. | 2013 Nov 1 | 24054122 |
New protein farnesyltransferase inhibitors in the 3-arylthiophene 2-carboxylic acid series: diversification of the aryl moiety by solid-phase synthesis. | 2013 Feb | 22233543 |
Synthesis and biological evaluation of new phenothiazine derivatives bearing a pyrazole unit as protein farnesyltransferase inhibitors. | 2012 Nov 15 | 23036952 |