Title | Date | PubMed ID |
Rational design, preparation, and characterization of a therapeutic enzyme mutant with improved stability and function for cocaine detoxification. | 2014 Aug 15 | 24919140 |
Cell permeable cocaine esterases constructed by chemical conjugation and genetic recombination. | 2012 May 7 | 22404344 |
The fate of bacterial cocaine esterase (CocE): an in vivo study of CocE-mediated cocaine hydrolysis, CocE pharmacokinetics, and CocE elimination. | 2012 Jan | 21990608 |
Subunit stabilization and polyethylene glycolation of cocaine esterase improves in vivo residence time. | 2011 Dec | 21890748 |
Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine. | 2011 Feb | 20971807 |
Design of high-activity mutants of human butyrylcholinesterase against (-)-cocaine: structural and energetic factors affecting the catalytic efficiency. | 2010 Oct 26 | 20886866 |
Characterization of a high-activity mutant of human butyrylcholinesterase against (-)-cocaine. | 2010 Sep 6 | 20060817 |
Structural analysis of thermostabilizing mutations of cocaine esterase. | 2010 Jul | 20436035 |
A thermally stable form of bacterial cocaine esterase: a potential therapeutic agent for treatment of cocaine abuse. | 2010 Apr | 20086035 |
Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats. | 2009 Nov | 19710369 |