TitleDatePubMed ID
Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties.2015 Apr 125728130
Activated factor XI increases the procoagulant activity of the extrinsic pathway by inactivating tissue factor pathway inhibitor.2015 Feb 2625587039
Pyridine and pyridinone-based factor XIa inhibitors.2015 Feb 1525592713
Phenylimidazoles as potent and selective inhibitors of coagulation factor XIa with in vivo antithrombotic activity.2014 Dec 1125405503
Site-specific N-glycosylation analysis of human factor XI: Identification of a noncanonical NXC glycosite.2014 Nov25092234
Allosteric inhibition of human factor XIa: discovery of monosulfated benzofurans as a class of promising inhibitors.2014 Apr 2424666186
Factor XI and traveling waves: the key to understanding coagulation in hemophilia?2013 Apr23547857
High-resolution crystal structures of factor XIa coagulation factor in complex with nonbasic high-affinity synthetic inhibitors.2012 Apr 122505407
Activated factor XI inhibits chemotaxis of polymorphonuclear leukocytes.2011 Nov21807745
The role of factor XIa (FXIa) catalytic domain exosite residues in substrate catalysis and inhibition by the Kunitz protease inhibitor domain of protease nexin 2.2011 Sep 921778227