TitleDatePubMed ID
Structural basis for the stabilization of the complement alternative pathway C3 convertase by properdin.2013 Aug 1323901101
Aurin tricarboxylic acid self-protects by inhibiting aberrant complement activation at the C3 convertase and C9 binding stages.2013 May23177218
Factor H-related protein 4 activates complement by serving as a platform for the assembly of alternative pathway C3 convertase via its interaction with C3b protein.2012 Jun 122518841
Functional analyses of complement convertases using C3 and C5-depleted sera.201223071769
Design and development of TT30, a novel C3d-targeted C3/C5 convertase inhibitor for treatment of human complement alternative pathway-mediated diseases.2011 Oct 2721860027
Access to the complement factor B scissile bond is facilitated by association of factor B with C3b protein.2011 Oct 1421862585
Essential role of factor B of the alternative complement pathway in complement activation and opsonophagocytosis during acute pneumococcal otitis media in mice.2011 Jul21502587
Complement alternative pathway acts as a positive feedback amplification of neutrophil activation.2011 Jan 2721063021
Structures of C3b in complex with factors B and D give insight into complement convertase formation.2010 Dec 2421205667
Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation.2010 Oct20852386